(E)-N-benzyl-2-cyano-3-(4-methoxyphenyl)prop-2-enamide

Base Information

Chemical Name:(E)-N-benzyl-2-cyano-3-(4-methoxyphenyl)prop-2-enamide
CAS No.:874655-85-3
Molecular Formula:C18H16N2O2
Molecular Weight:292.337
Hs Code.:
DSSTox Substance ID:DTXSID701325521
ChEMBL ID:CHEMBL1344022

Synonyms:(E)-N-benzyl-2-cyano-3-(4-methoxyphenyl)prop-2-enamide;874655-85-3;(2E)-N-benzyl-2-cyano-3-(4-methoxyphenyl)prop-2-enamide;MLS001164084;CHEMBL1344022;DTXSID701325521;HMS2852G09;STK977261;AKOS001049704;SMR000539399;AB00718552-01;EN300-12636663;SR-01000004773;SR-01000004773-1;N-benzyl-2-cyano-3-(4-methoxyphenyl)prop-2-enamide;Z44314433;N-BENZYL-2-CYANO-3-(4-METHOXYPHENYL)ACRYLAMIDE

Suppliers and Price of (E)-N-benzyl-2-cyano-3-(4-methoxyphenyl)prop-2-enamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of (E)-N-benzyl-2-cyano-3-(4-methoxyphenyl)prop-2-enamide

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:292.121177757
Heavy Atom Count:22
Complexity:435

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C=C(C#N)C(=O)NCC2=CC=CC=C2
Isomeric SMILES:COC1=CC=C(C=C1)/C=C(\C#N)/C(=O)NCC2=CC=CC=C2

Technology Process of (E)-N-benzyl-2-cyano-3-(4-methoxyphenyl)prop-2-enamide

There total 1 articles about (E)-N-benzyl-2-cyano-3-(4-methoxyphenyl)prop-2-enamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 10412-93-8
N-Benzylcyanoacetamide

: 123-11-5
4-methoxy-benzaldehyde

: 874655-85-3
(E)-N-benzyl-2-cyano-3-(4-methoxyphenyl)acrylamide

Guidance literature:: With pyrrolidine; In ethanol; at 20 ℃; for 1h;
DOI:10.1039/c4cc01231c

Reference yield: 80.0%

: 17424-21-4
5-methyl-hexadien-trans-2,4-al

: 874655-85-3
(E)-N-benzyl-2-cyano-3-(4-methoxyphenyl)acrylamide

: 1609623-81-5
(3S,4aS,8R,8aS)-2-benzyl-3-hydroxy-8-(4-methoxyphenyl)-6-methyl-1-oxo-2,3,4,4a,7,8-hexahydroisoquinoline-8a(1H)-carbonitrile

: C₂₅H₂₆N₂O₃

Guidance literature:: With (L)-2-{diphenyl[(triphenylsilyl)oxy]methyl}pyrrolidine; 4-nitro-benzoic acid; In 1,4-dioxane; at 70 ℃; stereoselective reaction;
DOI:10.1039/c4cc01231c

Reference yield: 79.0%

: 1666-17-7
benzaldehyde p-toluenesulfonylhydrazone

: 874655-85-3
(E)-N-benzyl-2-cyano-3-(4-methoxyphenyl)acrylamide

: N-benzyl-1-cyano-2-(4-methoxyphenyl)-3-phenylcyclopropanecarboxamide

Guidance literature:: With caesium carbonate; In 1,4-dioxane; at 70 ℃; diastereoselective reaction; Inert atmosphere;
DOI:10.1016/j.tetlet.2017.05.070