1-(4-Hydroxybenzyl)imidazole-2-thiol

Base Information

Chemical Name:1-(4-Hydroxybenzyl)imidazole-2-thiol
CAS No.:95333-64-5
Molecular Formula:C10H10 N2 O S
Molecular Weight:206.2642
Hs Code.:2933290090
DSSTox Substance ID:DTXSID20241812
Nikkaji Number:J271.836G
ChEMBL ID:CHEMBL164747
Mol file:95333-64-5.mol

Synonyms:1-(4-hydroxybenzyl)imidazole-2-thiol;1-HBIT

Suppliers and Price of 1-(4-Hydroxybenzyl)imidazole-2-thiol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-[(2-sulfanyl-1H-imidazol-1-yl)methyl]phenol
25mg
$ 310.00

TRC
4-[(2-sulfanyl-1H-imidazol-1-yl)methyl]phenol
2.5mg
$ 45.00

Total 3 raw suppliers

Chemical Property of 1-(4-Hydroxybenzyl)imidazole-2-thiol

Chemical Property:

Vapor Pressure:2.81E-06mmHg at 25°C
Boiling Point:378.8°Cat760mmHg
Flash Point:182.9°C
PSA：76.85000
Density:1.4g/cm³
LogP:1.92570
Storage Temp.:2-8°C
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:206.05138412
Heavy Atom Count:14
Complexity:247

Purity/Quality:: 4-[(2-sulfanyl-1H-imidazol-1-yl)methyl]phenol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CN2C=CNC2=S)O

Technology Process of 1-(4-Hydroxybenzyl)imidazole-2-thiol

There total 5 articles about 1-(4-Hydroxybenzyl)imidazole-2-thiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 1-(4'-acetoxybenzyl)-2-(acetylthio)imidazole

: 95333-64-5
1-(4'-hydroxybenzyl)-2-thioimidazole

Guidance literature:

Reference yield:

: 54879-50-4
(2,2-Dimethoxy-ethyl)-[1-(4-methoxy-phenyl)-meth-(Z)-ylidene]-amine

: 95333-64-5
1-(4'-hydroxybenzyl)-2-thioimidazole

Guidance literature:: Multi-step reaction with 3 steps

1: sodium borohydride / ethanol / 24 h / Ambient temperature

2: 12 N HCl / ethanol; H₂O / 2 h / Heating

3: BBr₃ / CH₂Cl₂ / 1.5 h

With hydrogenchloride; sodium tetrahydroborate; boron tribromide; In ethanol; dichloromethane; water;
DOI:10.1021/jm00386a008

Reference yield:

: 123-11-5
4-methoxy-benzaldehyde

: 95333-64-5
1-(4'-hydroxybenzyl)-2-thioimidazole

Guidance literature:: Multi-step reaction with 4 steps

1: 0.33 h / Heating

2: sodium borohydride / ethanol / 24 h / Ambient temperature

3: 12 N HCl / ethanol; H₂O / 2 h / Heating

4: BBr₃ / CH₂Cl₂ / 1.5 h

With hydrogenchloride; sodium tetrahydroborate; boron tribromide; In ethanol; dichloromethane; water;
DOI:10.1021/jm00386a008