5-Aminopentanamide

Base Information

• Chemical Name: 5-Aminopentanamide
• CAS No.: 13023-70-6
• Molecular Formula: C5H12N2O
• Molecular Weight: 116.163
• Hs Code.: 2924199090
• DSSTox Substance ID: DTXSID40331406
• Nikkaji Number: J38.134I
• Wikidata: Q27102839
• Metabolomics Workbench ID: 41893
• Mol file: 13023-70-6.mol

Synonyms:5-Aminopentanamide;13023-70-6;5-aminovaleramide;Pentanamide, 5-amino-;5-aminovaleric acid amide;C00990;SCHEMBL251459;SCHEMBL12065796;CHEBI:18120;DTXSID40331406;AC3685;MFCD19635703;AKOS013377038;SY247757;CS-0292935;EN300-150530;A1-04982;Q27102839

Chemical Property of 5-Aminopentanamide

Chemical Property:

• Vapor Pressure: 0.000693mmHg at 25°C
• Refractive Index: 1.471
• Boiling Point: 308.1 °C at 760 mmHg
• Flash Point: 140.2 °C
• PSA: 70.10000
• Density: 1.005 g/cm³
• LogP: 1.45070
• XLogP3: -1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 116.094963011
• Heavy Atom Count: 8
• Complexity: 72.8

Purity/Quality:

98% ^*data from raw suppliers

5-Aminopentanamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCN)CC(=O)N

Technology Process of 5-Aminopentanamide

There total 11 articles about 5-Aminopentanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl N-(5-amino-5-oxopentyl)carbamate (91419-47-5) → 5-aminopentanamide (13023-70-6)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; ethyl acetate; at 20 ℃; for 16h;

Reference yield:

5-dibenzylaminopentanamide (137089-43-1) → 5-aminopentanamide (13023-70-6)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 43h;

DOI:10.1248/cpb.39.1546

Reference yield:

5-bromovaleroyl chloride (4509-90-4) → 5-aminopentanamide (13023-70-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 28percent NH₄OH / H₂O / 0.75 h / 0 °C

2: K₂CO₃ / dimethylformamide / 87 h / Ambient temperature

3: H₂ / 10percent Pd/C / methanol / 43 h

With ammonium hydroxide; hydrogen; potassium carbonate; palladium on activated charcoal; In methanol; water; N,N-dimethyl-formamide;

DOI:10.1248/cpb.39.1546

upstream raw materials:

5-benzyloxycarbonylamino-valeric acid amide

2-amino-3,4,5,6-tetrahydropyridine

5-dibenzylaminopentanamide

5-bromovaleroyl chloride

Downstream raw materials:

piperidin-2-one

Nα-benzoyl-L-arginine