1-(3-Acetyl-5-iodophenyl)ethanone

Base Information

Chemical Name:1-(3-Acetyl-5-iodophenyl)ethanone
CAS No.:87533-53-7
Molecular Formula:C10H9IO2
Molecular Weight:288.085
Hs Code.:
DSSTox Substance ID:DTXSID80563441
Wikidata:Q82447882

Synonyms:87533-53-7;1-(3-ACETYL-5-IODOPHENYL)ETHANONE;SCHEMBL13307545;DTXSID80563441;AB77781;1,1'-(5-Iodo-1,3-phenylene)di(ethan-1-one)

Suppliers and Price of 1-(3-Acetyl-5-iodophenyl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-(3-Acetyl-5-iodophenyl)ethanone

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:287.96473
Heavy Atom Count:13
Complexity:203

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CC(=CC(=C1)I)C(=O)C

Technology Process of 1-(3-Acetyl-5-iodophenyl)ethanone

There total 4 articles about 1-(3-Acetyl-5-iodophenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13438-30-7
5-nitro-1,3-benzenedicarbonylchloride

: 87533-53-7
1,3-diacetyl-5-iodobenzene

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) Mg, CCl₄ / 1.) EtOH, Et₂O, 3 h, 2.) EtOH, Et₂O, THF, reflux, 16 h

2: 65 percent / H₂SO₄ / acetic acid; H₂O / 3.5 h / Heating

3: 89 percent / SnCl₂*2H₂O, conc. aq. HCl / 0.12 h / 95 °C

4: 1.) NaNO₂, 3percent aq. H₂SO₄, 2.) NaI / 1.) 0-5 deg C, 30 min, 2.) water, CH₂Cl₂, 5 deg C, 35 min

With hydrogenchloride; tetrachloromethane; sulfuric acid; magnesium; sodium iodide; tin(ll) chloride; sodium nitrite; In water; acetic acid;
DOI:10.1021/jm00367a007

Reference yield:

: 87555-27-9
tetraethyl 5-nitroisophthaloylbis(malonate)

: 87533-53-7
1,3-diacetyl-5-iodobenzene

Guidance literature:: Multi-step reaction with 3 steps

1: 65 percent / H₂SO₄ / acetic acid; H₂O / 3.5 h / Heating

2: 89 percent / SnCl₂*2H₂O, conc. aq. HCl / 0.12 h / 95 °C

3: 1.) NaNO₂, 3percent aq. H₂SO₄, 2.) NaI / 1.) 0-5 deg C, 30 min, 2.) water, CH₂Cl₂, 5 deg C, 35 min

With hydrogenchloride; sulfuric acid; sodium iodide; tin(ll) chloride; sodium nitrite; In water; acetic acid;
DOI:10.1021/jm00367a007

Reference yield:

: 87533-49-1
3,5-diacetyl aniline

: 87533-53-7
1,3-diacetyl-5-iodobenzene

Guidance literature:: With sulfuric acid; sodium iodide; sodium nitrite; Yield given. Multistep reaction; 1.) 0-5 deg C, 30 min, 2.) water, CH₂Cl₂, 5 deg C, 35 min;
DOI:10.1021/jm00367a007