4-Benzoylpiperazine-2,6-dione

Base Information

Chemical Name:4-Benzoylpiperazine-2,6-dione
CAS No.:87693-76-3
Molecular Formula:C11H10N2O3
Molecular Weight:218.212
Hs Code.:
DSSTox Substance ID:DTXSID60516970
Wikidata:Q82378659

Synonyms:4-Benzoylpiperazine-2,6-dione;87693-76-3;4-benzoyl-2,6-dioxopiperazine;SCHEMBL10997891;DTXSID60516970;OUSMICJGCXTDFC-UHFFFAOYSA-N;AKOS015427494

Suppliers and Price of 4-Benzoylpiperazine-2,6-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
4-benzoyl-2,6-Piperazinedione 97.00%
25G
$ 13300.00

AccelPharmtech
4-benzoyl-2,6-Piperazinedione 97.00%
5G
$ 5360.00

AccelPharmtech
4-benzoyl-2,6-Piperazinedione 97.00%
1G
$ 3120.00

Total 0 raw suppliers

Chemical Property of 4-Benzoylpiperazine-2,6-dione

Chemical Property:

PSA：69.97000
LogP:-0.00100
XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:218.06914219
Heavy Atom Count:16
Complexity:305

Purity/Quality:: 4-benzoyl-2,6-Piperazinedione 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=O)NC(=O)CN1C(=O)C2=CC=CC=C2

Technology Process of 4-Benzoylpiperazine-2,6-dione

There total 3 articles about 4-Benzoylpiperazine-2,6-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 36064-37-6
4-Benzoyl-piperazine-2,6-dione dioxime

: 87693-76-3
4-benzoylpiperazine-2,6-dione

Guidance literature:: With sodium nitrite; In water; acetic acid; at 0 ℃; for 24h;

Reference yield:

: 36130-48-0
N,N-bis(cyanomethyl)benzamide

: 87693-76-3
4-benzoylpiperazine-2,6-dione

Guidance literature:: Multi-step reaction with 2 steps

1: NH₂OH*HCl, K₂CO₃ / H₂O; methanol / 2 h / Heating

2: NaNO₂ / H₂O; acetic acid / 24 h / 0 °C

With hydroxylamine hydrochloride; potassium carbonate; sodium nitrite; In methanol; water; acetic acid;

Reference yield:

: 98-88-4
benzoyl chloride

: 87693-76-3
4-benzoylpiperazine-2,6-dione

Guidance literature:: Multi-step reaction with 3 steps

1: K₂CO₃ / H₂O; CH₂Cl₂ / 2 h / Ambient temperature

2: NH₂OH*HCl, K₂CO₃ / H₂O; methanol / 2 h / Heating

3: NaNO₂ / H₂O; acetic acid / 24 h / 0 °C

With hydroxylamine hydrochloride; potassium carbonate; sodium nitrite; In methanol; dichloromethane; water; acetic acid;