7-Bromo-2-methyl-1,2-dihydroisoquinolin-3(4H)-one

Base Information

Chemical Name:7-Bromo-2-methyl-1,2-dihydroisoquinolin-3(4H)-one
CAS No.:877265-10-6
Molecular Formula:C10H10BrNO
Molecular Weight:240.099
Hs Code.:2933790090
DSSTox Substance ID:DTXSID40695090
Wikidata:Q82624103
Mol file:877265-10-6.mol

Synonyms:877265-10-6;7-BROMO-2-METHYL-1,2-DIHYDROISOQUINOLIN-3(4H)-ONE;7-BROMO-2-METHYL-1,4-DIHYDROISOQUINOLIN-3-ONE;3(2H)-Isoquinolinone 7-bromo-1,4-dihydro-2-methyl-;7-Bromo-2-methyl-1,4-dihydroisoquinolin-3(2H)-one;3(2H)-Isoquinolinone, 7-bromo-1,4-dihydro-2-methyl-;7-bromo-2-methyl-1,2,3,4-tetrahydroisoquinolin-3-one;SCHEMBL14721435;DTXSID40695090;MFCD16875464;AKOS023808404;AS-35588;A862439;LogP

Suppliers and Price of 7-Bromo-2-methyl-1,2-dihydroisoquinolin-3(4H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
7-Bromo-2-methyl-1,2-dihydroisoquinolin-3(4H)-one 97%
1g
$ 412.00

Biosynth Carbosynth
7-Bromo-2-methyl-1,2-dihydroisoquinolin-3(4H)-one
100 mg
$ 300.00

Biosynth Carbosynth
7-Bromo-2-methyl-1,2-dihydroisoquinolin-3(4H)-one
50 mg
$ 200.00

Biosynth Carbosynth
7-Bromo-2-methyl-1,2-dihydroisoquinolin-3(4H)-one
250 mg
$ 450.00

Biosynth Carbosynth
7-Bromo-2-methyl-1,2-dihydroisoquinolin-3(4H)-one
1 g
$ 650.00

Biosynth Carbosynth
7-Bromo-2-methyl-1,2-dihydroisoquinolin-3(4H)-one
500 mg
$ 550.00

AstaTech
7-BROMO-2-METHYL-1,2-DIHYDROISOQUINOLIN-3(4H)-ONE 97%
5 / G
$ 1461.00

AstaTech
7-BROMO-2-METHYL-1,2-DIHYDROISOQUINOLIN-3(4H)-ONE 97%
1 / G
$ 487.00

AstaTech
7-BROMO-2-METHYL-1,2-DIHYDROISOQUINOLIN-3(4H)-ONE 97%
0.25 / G
$ 195.00

Alichem
7-Bromo-2-methyl-1,2-dihydroisoquinolin-3(4H)-one
250mg
$ 191.10

Total 10 raw suppliers

Chemical Property of 7-Bromo-2-methyl-1,2-dihydroisoquinolin-3(4H)-one

Chemical Property:

Vapor Pressure:0mmHg at 25°C
PSA：20.31000
LogP:1.90150
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:238.99458
Heavy Atom Count:13
Complexity:219

Purity/Quality:

97% ^*data from raw suppliers

7-Bromo-2-methyl-1,2-dihydroisoquinolin-3(4H)-one 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CC2=C(CC1=O)C=CC(=C2)Br

Technology Process of 7-Bromo-2-methyl-1,2-dihydroisoquinolin-3(4H)-one

There total 3 articles about 7-Bromo-2-methyl-1,2-dihydroisoquinolin-3(4H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 7713-76-0
2-(4-bromophenyl)-N-methylethanamide

: 877265-10-6
7-bromo-2-methyl-1,4-dihydro-2H-isoquinolin-3-one

Guidance literature:: With phosphorus pentoxide; In methanesulfonic acid; at 19 - 80 ℃; Large scale reaction;
DOI:10.1021/op9002533

Reference yield:

: 1878-68-8
2-(4-bromophenyl)-acetic acid

: 877265-10-6
7-bromo-2-methyl-1,4-dihydro-2H-isoquinolin-3-one

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride / 60 °C

2: tetrahydrofuran; dichloromethane

3: phosphoric acid / 160 °C

With thionyl chloride; phosphoric acid; In tetrahydrofuran; dichloromethane;
DOI:10.1021/op3000064

Reference yield:

: 37859-24-8
2-(4-bromophenyl)acetyl chloride

: 877265-10-6
7-bromo-2-methyl-1,4-dihydro-2H-isoquinolin-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran; dichloromethane

2: phosphoric acid / 160 °C

With phosphoric acid; In tetrahydrofuran; dichloromethane;
DOI:10.1021/op3000064