8-Chloro-5-phenylpyrido[3,2-d]pyridazine

Base Information

Chemical Name:8-Chloro-5-phenylpyrido[3,2-d]pyridazine
CAS No.:87987-99-3
Molecular Formula:C13H8ClN3
Molecular Weight:241.68
Hs Code.:
DSSTox Substance ID:DTXSID30443461
Wikidata:Q82261301

Synonyms:8-chloro-5-phenylpyrido[3,2-d]pyridazine;87987-99-3;SCHEMBL3651608;DTXSID30443461;IUFLJNRSXFHWLV-UHFFFAOYSA-N;8-CHLORO-5-PHENYLPYRIDO[2,3-D]PYRIDAZINE

Suppliers and Price of 8-Chloro-5-phenylpyrido[3,2-d]pyridazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 8-Chloro-5-phenylpyrido[3,2-d]pyridazine

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:241.0406750
Heavy Atom Count:17
Complexity:255

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NN=C(C3=C2C=CC=N3)Cl

Technology Process of 8-Chloro-5-phenylpyrido[3,2-d]pyridazine

There total 7 articles about 8-Chloro-5-phenylpyrido[3,2-d]pyridazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 87988-03-2
5-Phenylpyrido<2,3-d>pyridazin-8(7H)-one

: 87987-99-3
8-chloro-5-phenyl-pyrido[2,3-d]pyridazine

Guidance literature:: With trichlorophosphate; In pyridine; at 110 ℃;
DOI:10.1016/j.bmcl.2010.06.006

Reference yield:

: 211629-98-0
5-phenyl-pyrido[3,2-d][1,2]oxazin-8-one

: 87987-99-3
8-chloro-5-phenyl-pyrido[2,3-d]pyridazine

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate; acetic acid / Heating

2: 78 percent / phosphorus oxychloride; pyridine / 1 h / 110 °C

With pyridine; hydrazine hydrate; acetic acid; trichlorophosphate;
DOI:10.1080/00304940509354954

Reference yield:

: 23439-87-4
6-hydroxy-5H-pyrrolo[3,4-b]pyridine-5,7-(6H)-dione

: 87987-99-3
8-chloro-5-phenyl-pyrido[2,3-d]pyridazine

Guidance literature:: Multi-step reaction with 3 steps

1: 35.5 percent / AlCl₃ / 2 h / 80 °C

2: 80 percent / H₂NNH₂*H₂O / acetic acid / 2 h / Heating

3: 78 percent / POCl₃; pyridine / 1 h / 110 °C

With pyridine; aluminium trichloride; hydrazine hydrate; trichlorophosphate; In acetic acid; 1: Rearrangement / 2: Substitution / 3: Chlorination;
DOI:10.1080/00397919808004864