[(1R)-2,2-Diphenyl-1-(trimethylsilyl)cyclopropyl]methanol

Base Information

Chemical Name:[(1R)-2,2-Diphenyl-1-(trimethylsilyl)cyclopropyl]methanol
CAS No.:88035-73-8
Molecular Formula:C19H24OSi
Molecular Weight:296.484
Hs Code.:
DSSTox Substance ID:DTXSID80529906

Synonyms:88035-73-8;(R)-(2,2-Diphenyl-1-(trimethylsilyl)cyclopropyl)methanol;[(1R)-2,2-Diphenyl-1-(trimethylsilyl)cyclopropyl]methanol;DTXSID80529906

Suppliers and Price of [(1R)-2,2-Diphenyl-1-(trimethylsilyl)cyclopropyl]methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of [(1R)-2,2-Diphenyl-1-(trimethylsilyl)cyclopropyl]methanol

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:296.159641919
Heavy Atom Count:21
Complexity:342

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C[Si](C)(C)C1(CC1(C2=CC=CC=C2)C3=CC=CC=C3)CO
Isomeric SMILES:C[Si](C)(C)[C@@]1(CC1(C2=CC=CC=C2)C3=CC=CC=C3)CO

Technology Process of [(1R)-2,2-Diphenyl-1-(trimethylsilyl)cyclopropyl]methanol

There total 3 articles about [(1R)-2,2-Diphenyl-1-(trimethylsilyl)cyclopropyl]methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 88035-81-8
(R)-2,2-Diphenyl-1-trimethylsilanyl-cyclopropanecarboxylic acid methyl ester

: 88035-73-8
(-)-(R)-2,2-diphenyl-1-(hydroxymethyl)-1-(trimethylsilyl)cyclopropane

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; for 6h; Ambient temperature;
DOI:10.1021/ja00314a014

Reference yield:

: 7150-12-1
2,2-diphenyl-cyclopropanecarboxylic acid

: 88035-73-8
(-)-(R)-2,2-diphenyl-1-(hydroxymethyl)-1-(trimethylsilyl)cyclopropane

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) LDA / 1.) THF, hexane, 0 deg C, 3 h; 2.) THF, overnight, r.t.

2: 100 percent / diethyl ether

3: 91 percent / LiAlH₄ / diethyl ether / 6 h / Ambient temperature

With lithium aluminium tetrahydride; lithium diisopropyl amide; In diethyl ether;
DOI:10.1021/ja00314a014

Reference yield:

: 88082-48-8
2,2-Diphenyl-1-trimethylsilanyl-cyclopropanecarboxylic acid

: 88035-73-8
(-)-(R)-2,2-diphenyl-1-(hydroxymethyl)-1-(trimethylsilyl)cyclopropane

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / diethyl ether

2: 91 percent / LiAlH₄ / diethyl ether / 6 h / Ambient temperature

With lithium aluminium tetrahydride; In diethyl ether;
DOI:10.1021/ja00314a014