(1R)-2,2-Diphenyl-1-(trimethylsilyl)cyclopropane-1-carbaldehyde

Base Information

Chemical Name:(1R)-2,2-Diphenyl-1-(trimethylsilyl)cyclopropane-1-carbaldehyde
CAS No.:88035-75-0
Molecular Formula:C19H22OSi
Molecular Weight:294.469
Hs Code.:
DSSTox Substance ID:DTXSID00529908
Wikidata:Q82400668

Synonyms:88035-75-0;DTXSID00529908;(1R)-2,2-Diphenyl-1-(trimethylsilyl)cyclopropane-1-carbaldehyde

Suppliers and Price of (1R)-2,2-Diphenyl-1-(trimethylsilyl)cyclopropane-1-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R)-2,2-Diphenyl-1-(trimethylsilyl)cyclopropane-1-carbaldehyde

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:294.143991855
Heavy Atom Count:21
Complexity:367

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C[Si](C)(C)C1(CC1(C2=CC=CC=C2)C3=CC=CC=C3)C=O
Isomeric SMILES:C[Si](C)(C)[C@@]1(CC1(C2=CC=CC=C2)C3=CC=CC=C3)C=O

Technology Process of (1R)-2,2-Diphenyl-1-(trimethylsilyl)cyclopropane-1-carbaldehyde

There total 4 articles about (1R)-2,2-Diphenyl-1-(trimethylsilyl)cyclopropane-1-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 88035-73-8
(-)-(R)-2,2-diphenyl-1-(hydroxymethyl)-1-(trimethylsilyl)cyclopropane

: 88035-75-0
(-)-(R)-2,2-diphenyl-1-(trimethylsilyl)cyclopropanecarboxaldehyde

Guidance literature:: With manganese(IV) oxide; In dichloromethane; for 24h; Ambient temperature;
DOI:10.1021/ja00314a014

Reference yield:

: 7150-12-1
2,2-diphenyl-cyclopropanecarboxylic acid

: 88035-75-0
(-)-(R)-2,2-diphenyl-1-(trimethylsilyl)cyclopropanecarboxaldehyde

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) LDA / 1.) THF, hexane, 0 deg C, 3 h; 2.) THF, overnight, r.t.

2: 100 percent / diethyl ether

3: 91 percent / LiAlH₄ / diethyl ether / 6 h / Ambient temperature

4: 77 percent / MnO₂ / CH₂Cl₂ / 24 h / Ambient temperature

With manganese(IV) oxide; lithium aluminium tetrahydride; lithium diisopropyl amide; In diethyl ether; dichloromethane;
DOI:10.1021/ja00314a014

Reference yield:

: 88035-81-8
(R)-2,2-Diphenyl-1-trimethylsilanyl-cyclopropanecarboxylic acid methyl ester

: 88035-75-0
(-)-(R)-2,2-diphenyl-1-(trimethylsilyl)cyclopropanecarboxaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / LiAlH₄ / diethyl ether / 6 h / Ambient temperature

2: 77 percent / MnO₂ / CH₂Cl₂ / 24 h / Ambient temperature

With manganese(IV) oxide; lithium aluminium tetrahydride; In diethyl ether; dichloromethane;
DOI:10.1021/ja00314a014