4-METHYL-5-OXY-FURAZAN-3-CARBOXYLIC ACID

Base Information

• Chemical Name: 4-METHYL-5-OXY-FURAZAN-3-CARBOXYLIC ACID
• CAS No.: 37132-21-1
• Molecular Formula: C₄H₄N₂O₄
• Molecular Weight: 144.087
• Hs Code.: 2934999090
• Mol file: 37132-21-1.mol

Synonyms:4-Methyl-5-oxy-furazan-3-carboxylic acid;4-Methyl-1,2,5-oxadiazole 5-oxide-3-carboxylic Acid;4-methyl-1,2,5-oxadiazole-5-oxido-3-carboxylic acid;3-methyl-4-furoxancarboxylic acid;5-methyl-4-furoxancarboxylic acid;

Chemical Property of 4-METHYL-5-OXY-FURAZAN-3-CARBOXYLIC ACID

Chemical Property:

• Vapor Pressure: 1.2E-05mmHg at 25°C
• Boiling Point: 354.8°Cat760mmHg
• PKA: 2.06±0.32(Predicted)
• Flash Point: 168.4°C
• PSA: 88.79000
• Density: 1.77g/cm³
• LogP: 0.10970

Purity/Quality:

98%min ^*data from raw suppliers

4-Methyl-5-oxy-furazan-3-carboxylic acid ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

Useful:

Technology Process of 4-METHYL-5-OXY-FURAZAN-3-CARBOXYLIC ACID

There total 2 articles about 4-METHYL-5-OXY-FURAZAN-3-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

4-formyl-3-methylfuroxan (123953-16-2) → 3-methyl-4-furoxancarboxylic acid (37132-21-1)

Guidance literature:

With potassium permanganate; sulfuric acid; In acetone; for 12h; Ambient temperature;

DOI:10.1021/jm9803267

Reference yield:

4-methyl-5-oxy-furazan-3-carboxylic acid amide (37895-44-6) → 3-methyl-4-furoxancarboxylic acid (37132-21-1)

Guidance literature:

With potassium hydroxide;

Reference yield: 62.0%

3-methyl-4-furoxancarboxylic acid (37132-21-1) + N-amino-2-{2'-[(2'',6''-dichlorophenyl)amino]phenyl}acetamide (133239-50-6) → 4-[5-(2-(2,6-dichlorophenylamino)benzyl)-1,3,4-oxadiazol-2-yl]-3-methylfuroxan

Guidance literature:

With trichlorophosphate; for 6h; Reflux;

upstream raw materials:

4-methyl-5-oxy-furazan-3-carboxylic acid amide

4-formyl-3-methylfuroxan

Downstream raw materials:

4-(chlorocarbonyl)-3-methylfuroxan