N-amino-2-{2'-[(2'',6''-dichlorophenyl)amino]phenyl}acetamide

Base Information

• Chemical Name: N-amino-2-{2'-[(2'',6''-dichlorophenyl)amino]phenyl}acetamide
• CAS No.: 133239-50-6
• Molecular Formula: C₁₄H₁₃Cl₂N₃O
• Molecular Weight: 310.183
• Mol file: 133239-50-6.mol

Synonyms:N-amino-2-{2'-[(2'',6''-dichlorophenyl)amino]phenyl}acetamide

Chemical Property of N-amino-2-{2'-[(2'',6''-dichlorophenyl)amino]phenyl}acetamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-amino-2-{2'-[(2'',6''-dichlorophenyl)amino]phenyl}acetamide

There total 3 articles about N-amino-2-{2'-[(2'',6''-dichlorophenyl)amino]phenyl}acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2-[(2,6-dichlorophenyl)amino]phenylacetic acid methyl ester (15307-78-5) → N-amino-2-{2'-[(2'',6''-dichlorophenyl)amino]phenyl}acetamide (133239-50-6)

Guidance literature:

With hydrazine hydrate; In methanol; for 48h; Cooling with ice;

DOI:10.2174/1573406414666180321141555

Reference yield: 72.0%

ethyl 2-[2-(2,6-dichlorophenylamino)phenyl]acetate (15307-77-4) → N-amino-2-{2'-[(2'',6''-dichlorophenyl)amino]phenyl}acetamide (133239-50-6)

Guidance literature:

With hydrazine hydrate; In ethanol; for 20h; Heating;

DOI:10.1016/j.ejmech.2004.02.008

Reference yield:

diclofenac sodium (15307-79-6) → N-amino-2-{2'-[(2'',6''-dichlorophenyl)amino]phenyl}acetamide (133239-50-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 72 percent / sulfuric acid / 3 h / Heating

2: 72 percent / hydrazine hydrate / methanol / 2 h / Heating

With sulfuric acid; hydrazine hydrate; In methanol;

DOI:10.1016/j.bmc.2005.12.042

upstream raw materials:

2-[(2,6-dichlorophenyl)amino]phenylacetic acid methyl ester

ethyl 2-[2-(2,6-dichlorophenylamino)phenyl]acetate

diclofenac sodium

Downstream raw materials:

5-({2'-[(2'',6''-dichlorophenyl)amino]phenyl}methyl)-1,3,4-oxadiazole-2-thiol

1-(2-(2-(2,6-dichlorophenylamino)phenyl)acetyl)-4-p-tolylthiosemicarbazide

C₂₁H₁₇Cl₃N₄OS

C₂₁H₁₇Cl₂FN₄OS