2,4-DIAMINO-6-HYDROXY-PYRIMIDINE-5-CARBALDEHYDE

Base Information

• Chemical Name: 2,4-DIAMINO-6-HYDROXY-PYRIMIDINE-5-CARBALDEHYDE
• CAS No.: 88075-70-1
• Molecular Formula: C5H6N4O2
• Molecular Weight: 154.128
• Hs Code.: 2933599090
• Mol file: 88075-70-1.mol

Synonyms:2,4-Diamino-6-hydroxy-pyrimidine-5-carbaldehyde;2,3-DINITROOXY-BUTANEDIOIC ACID;2,4-diamino-5-formyl-6-oxo-1H-pyrimidine;

Chemical Property of 2,4-DIAMINO-6-HYDROXY-PYRIMIDINE-5-CARBALDEHYDE

Chemical Property:

• Vapor Pressure: 2.77E-08mmHg at 25°C
• Boiling Point: 449.8oC at 760 mmHg
• Flash Point: 225.8oC
• PSA: 115.12000
• Density: 1.88g/cm3
• LogP: 0.32150

Purity/Quality:

98%Min ^*data from raw suppliers

2,4-Diamino-6-hydroxy-pyrimidine-5-carbaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 43
• Safety Statements: 36/37

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4-DIAMINO-6-HYDROXY-PYRIMIDINE-5-CARBALDEHYDE

There total 3 articles about 2,4-DIAMINO-6-HYDROXY-PYRIMIDINE-5-CARBALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N-dimethyl-formamide (68-12-2,33513-42-7) + 2,6-diaminopyrimidin-4-ol (56-06-4) → 2,4-diamino-5-formyl-6-oxo(1H)-pyrimidine (88075-70-1) + dimethyl amine (124-40-3)

Guidance literature:

With sodium hydroxide; trichlorophosphate; Yield given. Multistep reaction; 1.) 40 deg C, 1 h, 2.) reflux;

Reference yield:

2-Amino-pyrimido[4,5-d]pyrimidin-4-ol (89890-99-3) → 2,4-diamino-5-formyl-6-oxo(1H)-pyrimidine (88075-70-1)

Guidance literature:

With hydrogenchloride; for 3h; Heating;

DOI:10.1021/jo00185a063

Reference yield:

2-Amino-pyrimido[4,5-d]pyrimidin-4-ol (89890-99-3) → 2,4-diamino-5-formyl-6-oxo(1H)-pyrimidine (88075-70-1) + N-(2-Amino-5-formyl-6-hydroxy-pyrimidin-4-yl)-formamide (89891-07-6) + C6H5N5O*H(1+) (89891-02-1) + C6H7N5O2*H(1+) (89891-05-4)

Guidance literature:

With hydrogenchloride; water; Product distribution; various reaction time, temperature, pH, solvent;

DOI:10.1021/jo00185a063

upstream raw materials:

2-Amino-pyrimido[4,5-d]pyrimidin-4-ol

N,N-dimethyl-formamide

2,6-diaminopyrimidin-4-ol

Downstream raw materials:

2,6-diaminopyrimidin-4-ol