2-phenyl-3,4-dihydro-5H-1,3,4-benzotriazepin-5-one

Base Information

• Chemical Name: 2-phenyl-3,4-dihydro-5H-1,3,4-benzotriazepin-5-one
• CAS No.: 30909-95-6
• Molecular Formula: C14H11 N3 O
• Molecular Weight: 237.2566
• Mol file: 30909-95-6.mol

Synonyms:5H-1,3,4-Benzotriazepin-5-one,1,4-dihydro-2-phenyl- (8CI,9CI); NSC 374521

Chemical Property of 2-phenyl-3,4-dihydro-5H-1,3,4-benzotriazepin-5-one

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.29g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-phenyl-3,4-dihydro-5H-1,3,4-benzotriazepin-5-one

There total 13 articles about 2-phenyl-3,4-dihydro-5H-1,3,4-benzotriazepin-5-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2-phenyl-1,2,3,4-tetrahydro-5H-1,3,4-benzotriazepin-5-one → 2-phenyl-1,4-dihydro-5H-1,3,4-benzotriazepin-5-one (30909-95-6)

Guidance literature:

With potassium permanganate; In acetone; for 8h; Heating;

DOI:10.1246/bcsj.59.1575

Reference yield: 74.0%

2-phenyl-4H-3,1-benzoxazin-4-one (1022-46-4) → 3,4-Dihydro-2-phenyl-5H-1,3,4-benzotriazepin-5-one (30909-95-6)

Guidance literature:

With hydrazine hydrate; In xylene; for 2h; Heating; other 2-aryl substituted 3,1-benzoxazine-4-ones;

Reference yield: 50.0%

isatoic anhydride (118-48-9) + benzoic acid hydrazide (613-94-5) → 3,4-Dihydro-2-phenyl-5H-1,3,4-benzotriazepin-5-one (30909-95-6)

Guidance literature:

With toluene-4-sulfonic acid; In acetic acid; for 9h; Heating;

DOI:10.1055/s-1983-30538

upstream raw materials:

isatoic anhydride

benzoic acid hydrazide

2-phenyl-4H-3,1-benzoxazin-4-one

1-(2'-aminobenzoyl)-2-benzoylhydrazine

Downstream raw materials:

3-amino-2-phenylquinazolin-4(3H)-one

N-(2-methyl-4-oxoquinazolin-4(3H)-yl)benzamide

N₃-acetylamino-2-phenyl-4(3H)-quinazolinone

2-phenyl-4(3H)-quinazolinone