1-(1,2-Diphenylethyl)piperazine

Base Information

Chemical Name:1-(1,2-Diphenylethyl)piperazine
CAS No.:88144-93-8
Molecular Formula:C18H22N2
Molecular Weight:266.386
Hs Code.:
ChEMBL ID:CHEMBL214237
DSSTox Substance ID:DTXSID00483036
Pharos Ligand ID:M474S9F1VDK6

Synonyms:1-(1,2-diphenylethyl)piperazine;CHEMBL214237;88144-93-8;SCHEMBL6171525;DTXSID00483036;N-(1,2-diphenylethyl)piperazine;BDBM50188059;PD178762

Suppliers and Price of 1-(1,2-Diphenylethyl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(1,2-Diphenylethyl)piperazine

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:266.178298710
Heavy Atom Count:20
Complexity:261

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)C(CC2=CC=CC=C2)C3=CC=CC=C3

Technology Process of 1-(1,2-Diphenylethyl)piperazine

There total 8 articles about 1-(1,2-Diphenylethyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 9.6%

: C₂₄H₃₂N₂*ClH

: 88144-93-8
1-(1,2-diphenylethyl)piperazine

Guidance literature:: C₂₄H₃₂N₂*ClH; With benzyl bromide; trifluoroacetic acid; zinc; In acetonitrile; for 0.0833333h; Inert atmosphere;

With benzaldehyde; 1-t-Butoxycarbonylpiperazine; In acetonitrile; at 20 ℃; for 1h;
DOI:10.1111/bph.15064

Reference yield:

: 937808-26-9
tert-butyl 4-(1,2-diphenylethyl)piperazine-1-carboxylate

: 88144-93-8
1-(1,2-diphenylethyl)piperazine

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃;
DOI:10.1016/j.bmcl.2006.05.051

Reference yield:

: 860302-53-0
1-tert-butyl 4-[1H-1,2,3-benzotriazol-1-yl (phenyl) methyl]piperazine-1-carboxylate

: 88144-93-8
1-(1,2-diphenylethyl)piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran

2: aq. TFA / CH₂Cl₂ / 20 °C

With trifluoroacetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmcl.2006.05.051