3-Bromopiperidin-2-one

Base Information

Chemical Name:3-Bromopiperidin-2-one
CAS No.:34433-86-8
Molecular Formula:C5H8 Br N O
Molecular Weight:178.029
Hs Code.:2933790090
European Community (EC) Number:252-023-2
DSSTox Substance ID:DTXSID80955983
Nikkaji Number:J250.889C
Mol file:34433-86-8.mol

Synonyms:3-Bromopiperidin-2-one;34433-86-8;EINECS 252-023-2;C5H8BrNO;MFCD09834399;3-Bromo-2-piperidinone;2-Piperidinone, 3-bromo-;a-Bromovalerolactam;3-Bromo-2-piperidone;3-Bromo-2-piperidinone #;C5-H8-Br-N-O;SCHEMBL5029979;DTXSID80955983;AKOS013464076;SB43052;AS-48296;SY105168;3-Bromo-3,4,5,6-tetrahydropyridin-2-ol;CS-0072629;FT-0757492;EN300-107267;F30215;A931174;F1905-0517

Suppliers and Price of 3-Bromopiperidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-bromopiperidin-2-one
10mg
$ 45.00

Matrix Scientific
3-Bromopiperidin-2-one 95%+
100mg
$ 118.00

Matrix Scientific
3-Bromopiperidin-2-one 95%+
500mg
$ 370.00

Matrix Scientific
3-Bromopiperidin-2-one 95%+
2.500g
$ 1374.00

Crysdot
3-Bromopiperidin-2-one 95+%
1g
$ 396.00

Crysdot
3-Bromopiperidin-2-one 95+%
5g
$ 1188.00

Chemenu
3-Bromopiperidin-2-one 95%
1g
$ 608.00

Biosynth Carbosynth
3-Bromopiperidin-2-one
100 mg
$ 250.00

Biosynth Carbosynth
3-Bromopiperidin-2-one
25 mg
$ 100.00

Biosynth Carbosynth
3-Bromopiperidin-2-one
50 mg
$ 160.00

Total 15 raw suppliers

Chemical Property of 3-Bromopiperidin-2-one

Chemical Property:

Vapor Pressure:0.000572mmHg at 25°C
Melting Point:147 °C(Solv: acetone (67-64-1))
Boiling Point:311.2°Cat760mmHg
PKA:14.94±0.40(Predicted)
Flash Point:142°C
PSA：32.59000
Density:1.57g/cm³
LogP:0.93580
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:176.97893
Heavy Atom Count:8
Complexity:105

Purity/Quality:

NLT 98% ^*data from raw suppliers

3-bromopiperidin-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(C(=O)NC1)Br

Technology Process of 3-Bromopiperidin-2-one

There total 5 articles about 3-Bromopiperidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 26228-95-5
3,3-dibromopiperidin-2-one

: 34433-86-8
3-bromo-2-piperidinone

Guidance literature:: With hydrogen; sodium acetate; palladium on activated charcoal; In acetic acid;

Reference yield: 40.0%

: 614754-00-6
2,5-dibromovaleramide

: 34433-86-8
3-bromo-2-piperidinone

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1016/S0957-4166(03)00548-2

Reference yield:

: 675-20-7
piperidin-2-one

: 34433-86-8
3-bromo-2-piperidinone

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / PCl₅, Br₂, ZnCl₂ / CHCl₃ / 5 h / Ambient temperature

2: 91 percent / H₂, AcONa / 10percent Pd-C / acetic acid

With phosphorus pentachloride; hydrogen; bromine; sodium acetate; zinc(II) chloride; palladium on activated charcoal; In chloroform; acetic acid;