3',5'-O-[Tetrakis(1-Methylethyl)-1,3-disiloxanediyl]-guanosine

Base Information

Chemical Name:3',5'-O-[Tetrakis(1-Methylethyl)-1,3-disiloxanediyl]-guanosine
CAS No.:88183-82-8
Molecular Formula:C22H39N5O5Si2
Molecular Weight:525.74600
Hs Code.:
Mol file:88183-82-8.mol

Synonyms:3',5'-O-Tetraisopropyldisiloxane Guanosine;

Suppliers and Price of 3',5'-O-[Tetrakis(1-Methylethyl)-1,3-disiloxanediyl]-guanosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3'',5''-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]guanosine
2mg
$ 75.00

TRC
3'',5''-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]guanosine
10 mg
$ 305.00

TRC
3'',5''-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]guanosine
5 mg
$ 165.00

Biosynth Carbosynth
3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine
2 mg
$ 142.76

Biosynth Carbosynth
3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine
5 mg
$ 259.55

Biosynth Carbosynth
3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine
10 mg
$ 471.90

Biosynth Carbosynth
3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine
50 mg
$ 1560.00

Biosynth Carbosynth
3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine
25 mg
$ 858.00

AK Scientific
9-[(6Ar,8R,9S)-9-hydroxy-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-2-amino-1H-purin-6-one
50mg
$ 2156.00

AK Scientific
9-[(6Ar,8R,9S)-9-hydroxy-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-2-amino-1H-purin-6-one
10mg
$ 687.00

Total 6 raw suppliers

Chemical Property of 3',5'-O-[Tetrakis(1-Methylethyl)-1,3-disiloxanediyl]-guanosine

Chemical Property:

PSA：147.73000
LogP:3.25890
Solubility.:Methanol

Purity/Quality:

97% ^*data from raw suppliers

3'',5''-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]guanosine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 3',5'-O-[Tetrakis(1-Methylethyl)-1,3-disiloxanediyl]-guanosine is used in the preparation of nucleotide analogs.

Technology Process of 3',5'-O-[Tetrakis(1-Methylethyl)-1,3-disiloxanediyl]-guanosine

There total 4 articles about 3',5'-O-[Tetrakis(1-Methylethyl)-1,3-disiloxanediyl]-guanosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 69304-37-6
1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane

: 961-07-9
2'-Deoxyguanosine

: 88183-82-8
3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-2'-deoxyguanosine

Guidance literature:: With pyridine; Ambient temperature;
DOI:10.1002/anie.199706471

Reference yield: 66.0%

: 88183-80-6
2'-O-(1-imidazolyl)thiocarbonyl-3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)guanosine

: 88183-82-8
3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-2'-deoxyguanosine

Guidance literature:: With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In toluene; at 100 ℃; for 3h;

Reference yield:

: 69304-44-5
3',5'-O-1,1,3,3-tetraisopropyldisiloxan-1,3-diyl-guanosine

: 88183-82-8
3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-2'-deoxyguanosine

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / 1,2-dichloro-ethane / 3 h / Heating

2: 66 percent / tri-n-butyltin hydride, azobisisobutyronitrile / toluene / 3 h / 100 °C

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In 1,2-dichloro-ethane; toluene;