4'-Fluoro-2-hydroxy-4-(4-(2-pyridyl)-1-piperazinyl)butyrophenone

Base Information

Chemical Name:4'-Fluoro-2-hydroxy-4-(4-(2-pyridyl)-1-piperazinyl)butyrophenone
CAS No.:51037-58-2
Molecular Formula:C19H22FN3O2
Molecular Weight:343.3953
Hs Code.:
DSSTox Substance ID:DTXSID00965322
Nikkaji Number:J67.463J

Synonyms:BRN 0846370;4'-Fluoro-2-hydroxy-4-(4-(2-pyridyl)-1-piperazinyl)butyrophenone;1-(4-Fluorophenyl)-2-hydroxy-4-(4-(2-pyridyl)-1-piperazinyl)-1-butanone;BUTYROPHENONE, 4'-FLUORO-2-HYDROXY-4-(4-(2-PYRIDYL)-1-PIPERAZINYL)-;5-23-03-00042 (Beilstein Handbook Reference);51037-58-2;SCHEMBL11829798;C19H22FN3O2;DTXSID00965322;C19-H22-F-N3-O2;LS-48376;4'-Fluoro-alpha-hydroxy-gamma-[4-(2-pyridyl)-1-piperazinyl]butyrophenone;1-(4-Fluorophenyl)-2-hydroxy-4-[4-(pyridin-2-yl)piperazin-1-yl]butan-1-one

Suppliers and Price of 4'-Fluoro-2-hydroxy-4-(4-(2-pyridyl)-1-piperazinyl)butyrophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4'-Fluoro-2-hydroxy-4-(4-(2-pyridyl)-1-piperazinyl)butyrophenone

Chemical Property:

Vapor Pressure:1.17E-12mmHg at 25°C
Boiling Point:543.8°Cat760mmHg
Flash Point:282.7°C
Density:1.234g/cm³
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:343.16960512
Heavy Atom Count:25
Complexity:421

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CCC(C(=O)C2=CC=C(C=C2)F)O)C3=CC=CC=N3

Technology Process of 4'-Fluoro-2-hydroxy-4-(4-(2-pyridyl)-1-piperazinyl)butyrophenone

There total 4 articles about 4'-Fluoro-2-hydroxy-4-(4-(2-pyridyl)-1-piperazinyl)butyrophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51037-74-2
1-p-fluorobenzoyl-1-bromo-3-chloro-propane

: 51037-58-2
1-(4-fluorophenyl)-2-hydroxy-4-<4-(2-pyridyl)-1-piperazinyl>-1-butanone

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / methanol / 24 h / Ambient temperature

2: potassium iodide / toluene / 20 h / Heating

With potassium iodide; In methanol; toluene;

Reference yield:

: 3874-54-2,41167-07-1
4-(4-fluorophenyl)-4-oxo-n-butyl chloride

: 51037-58-2
1-(4-fluorophenyl)-2-hydroxy-4-<4-(2-pyridyl)-1-piperazinyl>-1-butanone

Guidance literature:: Multi-step reaction with 3 steps

1: 85 percent / bromine, CaCO₃ / CHCl₃ / 8 h / Ambient temperature

2: 81 percent / methanol / 24 h / Ambient temperature

3: potassium iodide / toluene / 20 h / Heating

With bromine; calcium carbonate; potassium iodide; In methanol; chloroform; toluene;