Phenyl[3-(piperidine-1-sulfonyl)pyridin-4-yl]methanone

Base Information

Chemical Name:Phenyl[3-(piperidine-1-sulfonyl)pyridin-4-yl]methanone
CAS No.:88184-96-7
Molecular Formula:C17H18N2O3S
Molecular Weight:330.408
Hs Code.:
DSSTox Substance ID:DTXSID40516918
Wikidata:Q82378577

Synonyms:88184-96-7;Phenyl[3-(piperidine-1-sulfonyl)pyridin-4-yl]methanone;DTXSID40516918

Suppliers and Price of Phenyl[3-(piperidine-1-sulfonyl)pyridin-4-yl]methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Phenyl[3-(piperidine-1-sulfonyl)pyridin-4-yl]methanone

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:330.10381361
Heavy Atom Count:23
Complexity:502

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCN(CC1)S(=O)(=O)C2=C(C=CN=C2)C(=O)C3=CC=CC=C3

Technology Process of Phenyl[3-(piperidine-1-sulfonyl)pyridin-4-yl]methanone

There total 4 articles about Phenyl[3-(piperidine-1-sulfonyl)pyridin-4-yl]methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 88184-87-6
Phenyl-[3-(piperidine-1-sulfonyl)-pyridin-4-yl]-methanol

: 88184-96-7
Phenyl-[3-(piperidine-1-sulfonyl)-pyridin-4-yl]-methanone

Guidance literature:: With manganese(IV) oxide; In toluene; for 24h; Heating;
DOI:10.1055/s-1983-30528

Reference yield:

: 636-73-7
3-pyridinesulfonic acid

: 88184-96-7
Phenyl-[3-(piperidine-1-sulfonyl)-pyridin-4-yl]-methanone

Guidance literature:: Multi-step reaction with 4 steps

1: PCl₅ / 3 h / Heating

2: benzene / 0.5 h / 0 °C

3: 1.) butyllithium, diisopropylamine / 1.) Et₂O, -70 deg C, 1 h; 2.) Et₂O, -70 deg C, 2 h

4: 100 percent / MnO₂ / toluene / 24 h / Heating

With manganese(IV) oxide; n-butyllithium; phosphorus pentachloride; diisopropylamine; In toluene; benzene;
DOI:10.1055/s-1983-30528

Reference yield:

: 16133-25-8
Pyridine-3-sulfonyl chloride

: 88184-96-7
Phenyl-[3-(piperidine-1-sulfonyl)-pyridin-4-yl]-methanone

Guidance literature:: Multi-step reaction with 3 steps

1: benzene / 0.5 h / 0 °C

2: 1.) butyllithium, diisopropylamine / 1.) Et₂O, -70 deg C, 1 h; 2.) Et₂O, -70 deg C, 2 h

3: 100 percent / MnO₂ / toluene / 24 h / Heating

With manganese(IV) oxide; n-butyllithium; diisopropylamine; In toluene; benzene;
DOI:10.1055/s-1983-30528