Heptylamine, 7-fluoro-

Base Information

• Chemical Name: Heptylamine, 7-fluoro-
• CAS No.: 353-21-9
• Molecular Formula: C7H16FN
• Molecular Weight: 133.24
• Hs Code.: 2921199090
• DSSTox Substance ID: DTXSID50188802
• Nikkaji Number: J73.678C
• Wikidata: Q83060651
• Mol file: 353-21-9.mol

Synonyms:7-Fluoroheptylamine;7-fluoroheptan-1-amine;HEPTYLAMINE, 7-FLUORO-;353-21-9;BRN 1734233;4-04-00-00742 (Beilstein Handbook Reference);C7H16FN;DTXSID50188802;C7-H16-F-N;AKOS006341115;AT34675;LS-74726

Chemical Property of Heptylamine, 7-fluoro-

Chemical Property:

• Vapor Pressure: 1.4mmHg at 25°C
• Boiling Point: 171.4°Cat760mmHg
• Flash Point: 64.6°C
• PSA: 26.02000
• Density: 0.869g/cm³
• LogP: 2.56540
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 133.126677677
• Heavy Atom Count: 9
• Complexity: 48.2

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCCN)CCCF

Technology Process of Heptylamine, 7-fluoro-

There total 3 articles about Heptylamine, 7-fluoro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7-Fluoroheptanenitrile (334-44-1) → 1-Amino-7-fluoroheptane (353-21-9)

Guidance literature:

With lithium aluminium tetrahydride; diethyl ether;

DOI:10.1021/ja01595a059

Reference yield:

1 ,6-dibromohexane (629-03-8) → 1-Amino-7-fluoroheptane (353-21-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 11 percent / KF / bis-(2-hydroxy-ethyl) ether / 160 °C / 3.9 Torr

2: 64 percent / aq. ethanol / 18 h / Heating

3: NaBH₄, CoCl₂*6H₂O / methanol / 2 h / Ambient temperature

With potassium fluoride; sodium tetrahydroborate; cobalt(II) chloride; In methanol; ethanol; diethylene glycol;

DOI:10.1016/S0022-1139(96)03457-4

Reference yield:

6-fluoro-1-bromo-hexane (373-28-4) → 1-Amino-7-fluoroheptane (353-21-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 64 percent / aq. ethanol / 18 h / Heating

2: NaBH₄, CoCl₂*6H₂O / methanol / 2 h / Ambient temperature

With sodium tetrahydroborate; cobalt(II) chloride; In methanol; ethanol;

DOI:10.1016/S0022-1139(96)03457-4

upstream raw materials:

7-Fluoroheptanenitrile

1 ,6-dibromohexane

6-fluoro-1-bromo-hexane

Refernces