Tetradecanoic acid, 3-oxo-

Base Information

• Chemical Name: Tetradecanoic acid, 3-oxo-
• CAS No.: 88222-72-4
• Molecular Formula: C14H26O3
• Molecular Weight: 242.359
• Mol file: 88222-72-4.mol

Synonyms:3-Oxo-tetradecansaeure;3CO Myristic acid;3-ketomyristic acid;Tetradecanoic acid,3-oxo;3-oxo-tetradecanoic acid;3-oxomyristic acid;3-Oxotetradecanoate;

Chemical Property of Tetradecanoic acid, 3-oxo-

Chemical Property:

• Melting Point: 93-94℃
• PSA: 54.37000
• LogP: 3.95110

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Tetradecanoic acid, 3-oxo-

There total 9 articles about Tetradecanoic acid, 3-oxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

benzyl 3-oxotetradecanoate (151663-65-9) → 3-oxomyristic acid (88222-72-4)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 3h; under 760.051 Torr;

DOI:10.1002/anie.201809539

Reference yield:

undecyl cyanide (2437-25-4) → 3-oxomyristic acid (88222-72-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) Zn dust, 2.) 1.0 aq. HCl / 1.) THF, reflux

2: H₂ / Pd(OH)2/C / methanol

With hydrogenchloride; hydrogen; zinc; palladium dihydroxide; In methanol;

DOI:10.1021/ja00087a075

Reference yield:

n-dodecanoyl chloride (112-16-3) + bis(trimethylsilyl) malonate (18457-04-0) → 3-oxomyristic acid (88222-72-4)

Guidance literature:

bis(trimethylsilyl) malonate; With n-butyllithium; In diethyl ether; at -78 - -10 ℃;

n-dodecanoyl chloride; In diethyl ether; at -10 ℃; for 0.5h;

DOI:10.1021/ja0530321

upstream raw materials:

methyl 3-oxotetradecanoate

ethyl 3-oxotetradecanoate

cycl-isopropylidene malonate

n-dodecanoyl chloride

Downstream raw materials:

methyl 3-oxotetradecanoate

N-(3-oxotetradecanoyl)-L-homoserine lactone

3-hydroxytetradecanoic acid

(+/-)-3-hydroxytetradecanoic acid methyl ester