(S)-2-[1-Benzyl-2-(tert-butoxycarbonyl)hydrazino]-3-methylbutyric acid

Base Information

Chemical Name:(S)-2-[1-Benzyl-2-(tert-butoxycarbonyl)hydrazino]-3-methylbutyric acid
CAS No.:188777-46-0
Molecular Formula:C17H25N2O4-
Molecular Weight:321.3919
Hs Code.:
Nikkaji Number:J1.995.532J
Mol file:188777-46-0.mol

Synonyms:(S)-2-[1-Benzyl-2-(tert-butoxycarbonyl)hydrazino]-3-methylbutyric acid

Suppliers and Price of (S)-2-[1-Benzyl-2-(tert-butoxycarbonyl)hydrazino]-3-methylbutyric acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (S)-2-[1-Benzyl-2-(tert-butoxycarbonyl)hydrazino]-3-methylbutyric acid

Chemical Property:

Melting Point:108-112 °C
Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：85.19000
Density:g/cm³
LogP:1.90720
Storage Temp.:0-6°C
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:322.18925731
Heavy Atom Count:23
Complexity:398

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(C(=O)O)N(CC1=CC=CC=C1)NC(=O)OC(C)(C)C
Isomeric SMILES:CC(C)[C@@H](C(=O)O)N(CC1=CC=CC=C1)NC(=O)OC(C)(C)C

Technology Process of (S)-2-[1-Benzyl-2-(tert-butoxycarbonyl)hydrazino]-3-methylbutyric acid

There total 7 articles about (S)-2-[1-Benzyl-2-(tert-butoxycarbonyl)hydrazino]-3-methylbutyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 15363-84-5
(S)-2-(benzylamino)-3-methylbutanoic acid

: 150884-56-3,158807-35-3
N-tert-butyloxycarbonyl-3-(4-cyanophenyl)oxaziridine

: 188777-46-0,313672-19-4
(S)-2-{1-benzyl-2-[(tert-butoxy)carbonyl]hydrazino}-3-methylbutanoic acid

Guidance literature:: With tetraethylammonium hydroxide; 1.) MeOH, 2.) CH₂Cl₂;
DOI:10.1002/chem.19970031019

Reference yield:

: 1070-19-5
N-(tert-butyloxycarbonyl) azide

: 188777-46-0,313672-19-4
(S)-2-{1-benzyl-2-[(tert-butoxy)carbonyl]hydrazino}-3-methylbutanoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 92 percent / diethyl ether

2: 75 percent / toluene / 17 h / Heating

3: LiMCPBA / CH₂Cl₂ / 2 h / -78 °C

4: 68 percent / Et₄NOH / 1.) MeOH, 2.) CH₂Cl₂

With LiMCPBA; tetraethylammonium hydroxide; In diethyl ether; dichloromethane; toluene;
DOI:10.1002/chem.19970031019

Reference yield:

: 68014-21-1
triphenyl(t-butoxycarbonylimino)phosphorane

: 188777-46-0,313672-19-4
(S)-2-{1-benzyl-2-[(tert-butoxy)carbonyl]hydrazino}-3-methylbutanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / toluene / 17 h / Heating

2: LiMCPBA / CH₂Cl₂ / 2 h / -78 °C

3: 68 percent / Et₄NOH / 1.) MeOH, 2.) CH₂Cl₂

With LiMCPBA; tetraethylammonium hydroxide; In dichloromethane; toluene;
DOI:10.1002/chem.19970031019