Dimethyl 2,6-dimethyl-4-(4-methylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Base Information

Chemical Name:Dimethyl 2,6-dimethyl-4-(4-methylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate
CAS No.:73257-48-4
Molecular Formula:C18H21 N O4
Molecular Weight:315.369
Hs Code.:
DSSTox Substance ID:DTXSID10973175
Nikkaji Number:J509.713D
ChEMBL ID:CHEMBL25934,CHEMBL2281648
Mol file:73257-48-4.mol

Synonyms:1,4-dihydro-2,6-dimethyl-4-(4-methylphenyl)-3,5-pyridinedicarboxylic acid dimethyl ester;2,6-dimethyl-3,5-dicarbomethoxy-4-(4-methylphenyl)-1,4-dihydropyridine

Suppliers and Price of Dimethyl 2,6-dimethyl-4-(4-methylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Dimethyl 2,6-dimethyl-4-(4-methylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate
500mg
$ 158.00

Biosynth Carbosynth
Dimethyl 2,6-dimethyl-4-(4-methylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate
2 g
$ 289.00

Biosynth Carbosynth
Dimethyl 2,6-dimethyl-4-(4-methylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate
1 g
$ 170.00

Biosynth Carbosynth
Dimethyl 2,6-dimethyl-4-(4-methylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate
500 mg
$ 100.00

Biosynth Carbosynth
Dimethyl 2,6-dimethyl-4-(4-methylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate
250 mg
$ 57.50

Biosynth Carbosynth
Dimethyl 2,6-dimethyl-4-(4-methylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate
5 g
$ 578.00

American Custom Chemicals Corporation
2,6-DIMETHYL-4-P-TOLYL-1,4-DIHYDRO-PYRIDINE-3,5-DICARBOXYLIC ACID DIMETHYL ESTER 95.00%
5MG
$ 497.87

Total 2 raw suppliers

Chemical Property of Dimethyl 2,6-dimethyl-4-(4-methylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Chemical Property:

Vapor Pressure:5.75E-08mmHg at 25°C
Boiling Point:440.7°C at 760 mmHg
Flash Point:220.4°C
PSA：64.63000
Density:1.139g/cm³
LogP:2.90460
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:315.14705815
Heavy Atom Count:23
Complexity:515

Purity/Quality:

98%min ^*data from raw suppliers

Dimethyl 2,6-dimethyl-4-(4-methylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2C(=C(NC(=C2C(=O)OC)C)C)C(=O)OC

Technology Process of Dimethyl 2,6-dimethyl-4-(4-methylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate

There total 6 articles about Dimethyl 2,6-dimethyl-4-(4-methylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 104-87-0
4-methyl-benzaldehyde

: 105-45-3
acetoacetic acid methyl ester

: 73257-48-4
2,6-dimethyl-3,5-dimethoxycarbonyl-4-(4-methylphenyl)-1,4-dihydropyridine

Guidance literature:: With ammonium acetate; at 90 ℃; for 1.66667h; Neat (no solvent);
DOI:10.1002/adsc.201100352

Reference yield: 95.0%

: 589-18-4
4-Methylbenzyl alcohol

: 105-45-3
acetoacetic acid methyl ester

: 73257-48-4
2,6-dimethyl-3,5-dimethoxycarbonyl-4-(4-methylphenyl)-1,4-dihydropyridine

Guidance literature:: With ammonium hydroxide; hydrogen bromide; dimethyl sulfoxide; In water; at 75 ℃; for 2.53333h;
DOI:10.1016/j.tetlet.2018.10.010