5-Bromo-2-(2-methylphenyl)pyridine

Base Information

Chemical Name:5-Bromo-2-(2-methylphenyl)pyridine
CAS No.:88345-94-2
Molecular Formula:C12H10BrN
Molecular Weight:248.122
Hs Code.:
European Community (EC) Number:632-969-6
DSSTox Substance ID:DTXSID50520268
Nikkaji Number:J3.273.850H
Wikidata:Q82384062

Synonyms:5-bromo-2-o-tolylpyridine;5-Bromo-2-(2-methylphenyl)pyridine;88345-94-2;SCHEMBL2005454;DTXSID50520268;QKYDTWSRQURVQZ-UHFFFAOYSA-N;MFCD14707250;AKOS015941887;CS-0193158;E91039;A1-07932;J-516989

Suppliers and Price of 5-Bromo-2-(2-methylphenyl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
5-Bromo-2-o-tolylpyridine 95%
1g
$ 908.00

Matrix Scientific
5-Bromo-2-o-tolylpyridine 95%
5g
$ 1568.00

AOBChem
5-Bromo-2-(2-methylphenyl)pyridine 97%
500mg
$ 301.00

AK Scientific
5-Bromo-2-(2-methylphenyl)pyridine
1g
$ 1275.00

A1 Biochem Labs
5-Bromo-2-o-tolylpyridine 95%
5 g
$ 950.00

A1 Biochem Labs
5-Bromo-2-o-tolylpyridine 95%
1 g
$ 550.00

Total 5 raw suppliers

Chemical Property of 5-Bromo-2-(2-methylphenyl)pyridine

Chemical Property:

PSA：12.89000
LogP:3.81950
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:246.99966
Heavy Atom Count:14
Complexity:183

Purity/Quality:

99% ^*data from raw suppliers

5-Bromo-2-o-tolylpyridine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1C2=NC=C(C=C2)Br

Technology Process of 5-Bromo-2-(2-methylphenyl)pyridine

There total 4 articles about 5-Bromo-2-(2-methylphenyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 624-28-2
2,5-dibromopyridine

: 16419-60-6
2-Methylphenylboronic acid

: 88345-94-2
5-bromo-2-(2-methylphenyl)pyridine

Guidance literature:: With palladium diacetate; potassium carbonate; triphenylphosphine; In methanol; acetonitrile; at 50 ℃; for 24h; regioselective reaction; Inert atmosphere;
DOI:10.1016/j.tet.2013.10.065

Reference yield:

: 626-55-1,163928-56-1
3-Bromopyridine

: 88345-94-2
5-bromo-2-(2-methylphenyl)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 0.25 h / -20 °C

2: 2) o-chloranil / 1) THF, -20 deg C, 15 min, 2) toluene, reflux, 6 h

With o-tetrachloroquinone; In tetrahydrofuran;

Reference yield:

: 1885-14-9
phenyl chloroformate

: 88345-94-2
5-bromo-2-(2-methylphenyl)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 0.25 h / -20 °C

2: 2) o-chloranil / 1) THF, -20 deg C, 15 min, 2) toluene, reflux, 6 h

With o-tetrachloroquinone; In tetrahydrofuran;