N-(2-(Furan-2-yl)-2-oxoethyl)-4-methoxybenzamide

Base Information

Chemical Name:N-(2-(Furan-2-yl)-2-oxoethyl)-4-methoxybenzamide
CAS No.:88352-95-8
Molecular Formula:C14H13NO4
Molecular Weight:259.262
Hs Code.:
DSSTox Substance ID:DTXSID40549009
Wikidata:Q82427873

Synonyms:88352-95-8;N-(2-(Furan-2-yl)-2-oxoethyl)-4-methoxybenzamide;N-[2-(Furan-2-yl)-2-oxoethyl]-4-methoxybenzamide;SCHEMBL10724596;DTXSID40549009;UENJRTOGKKSMSB-UHFFFAOYSA-N;N-(4-methoxybenzoyl)-(2-furylcarbonyl)methylamine

Suppliers and Price of N-(2-(Furan-2-yl)-2-oxoethyl)-4-methoxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(2-(Furan-2-yl)-2-oxoethyl)-4-methoxybenzamide

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:259.08445790
Heavy Atom Count:19
Complexity:323

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C(=O)NCC(=O)C2=CC=CO2

Technology Process of N-(2-(Furan-2-yl)-2-oxoethyl)-4-methoxybenzamide

There total 1 articles about N-(2-(Furan-2-yl)-2-oxoethyl)-4-methoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.3%

: 88352-86-7
(furan-2-ylcarbonyl)methylamine hydrochloride

: 100-07-2
4-methoxy-benzoyl chloride

: 88352-95-8
N-(4-methoxybenzoyl)-(furan-2-ylcarbonyl)methylamine

Guidance literature:: With sodium hydrogencarbonate; In water; ethyl acetate; Ambient temperature;
DOI:10.1021/jm00401a021

Reference yield: 73.0%

: 105-36-2
ethyl bromoacetate

: 88352-95-8
N-(4-methoxybenzoyl)-(furan-2-ylcarbonyl)methylamine

: 88352-49-2
ethyl 3-(4-methoxybenzoylamino)-3-(furan-2-ylcarbonyl)propionate

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; paraffin; 1.) -50 - -40 deg C, 20 min, 2.) -40 to 10 deg C, 30 min;
DOI:10.1021/jm00401a021

Reference yield:

: 88352-95-8
N-(4-methoxybenzoyl)-(furan-2-ylcarbonyl)methylamine

: 88352-74-3
[5-Furan-2-yl-2-(4-methoxy-phenyl)-oxazol-4-yl]-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 73 percent / NaH / paraffin; dimethylformamide / 1.) -50 - -40 deg C, 20 min, 2.) -40 to 10 deg C, 30 min

2: 32 percent / thionyl chloride, pyridine / CHCl₃ / 6 h / Heating

3: 82 percent / KOH / methanol; H₂O / 8 h / 50 °C

With pyridine; potassium hydroxide; thionyl chloride; sodium hydride; In methanol; chloroform; water; N,N-dimethyl-formamide; paraffin;
DOI:10.1021/jm00401a021