4-Fluoro-N-(2-(furan-3-yl)-2-oxoethyl)benzamide

Base Information

Chemical Name:4-Fluoro-N-(2-(furan-3-yl)-2-oxoethyl)benzamide
CAS No.:88353-01-9
Molecular Formula:C13H10FNO3
Molecular Weight:247.226
Hs Code.:
DSSTox Substance ID:DTXSID80549447
Wikidata:Q82428487

Synonyms:88353-01-9;4-Fluoro-N-(2-(furan-3-yl)-2-oxoethyl)benzamide;4-Fluoro-N-[2-(furan-3-yl)-2-oxoethyl]benzamide;SCHEMBL10727748;DTXSID80549447;ZCOJGBYZZVUHFY-UHFFFAOYSA-N;N-(4-fluorobenzoyl)-(3-furylcarbonyl)methylamine

Suppliers and Price of 4-Fluoro-N-(2-(furan-3-yl)-2-oxoethyl)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-Fluoro-N-(2-(furan-3-yl)-2-oxoethyl)benzamide

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:247.06447134
Heavy Atom Count:18
Complexity:313

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)NCC(=O)C2=COC=C2)F

Technology Process of 4-Fluoro-N-(2-(furan-3-yl)-2-oxoethyl)benzamide

There total 1 articles about 4-Fluoro-N-(2-(furan-3-yl)-2-oxoethyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 403-43-0
4-fluorobenzoyl chloride

: 88352-90-3
aminomethyl 3-furyl ketone hydrochloride

: 88353-01-9
N-(4-fluorobenzoyl)-(furan-3-ylcarbonyl)methylamine

Guidance literature:: With sodium hydrogencarbonate; In water; ethyl acetate; Ambient temperature;
DOI:10.1021/jm00401a021

Reference yield: 70.0%

: 105-36-2
ethyl bromoacetate

: 88353-01-9
N-(4-fluorobenzoyl)-(furan-3-ylcarbonyl)methylamine

: 88352-59-4
ethyl 3-(4-fluorobenzoylamino)-3-(furan-3-ylcarbonyl)propionate

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; paraffin; 1.) -50 - -40 deg C, 20 min, 2.) -40 to 10 deg C, 30 min;
DOI:10.1021/jm00401a021

Reference yield:

: 88353-01-9
N-(4-fluorobenzoyl)-(furan-3-ylcarbonyl)methylamine

: 88352-81-2
[2-(4-Fluoro-phenyl)-5-furan-3-yl-oxazol-4-yl]-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / NaH / paraffin; dimethylformamide / 1.) -50 - -40 deg C, 20 min, 2.) -40 to 10 deg C, 30 min

2: 66 percent / phosphoryl chloride / dimethylformamide / 8 h / Ambient temperature

3: 85 percent / KOH / methanol; H₂O / 8 h / 50 °C

With potassium hydroxide; sodium hydride; trichlorophosphate; In methanol; water; N,N-dimethyl-formamide; paraffin;
DOI:10.1021/jm00401a021