1-Benzyl-5-oxopyrrolidin-2-yl acetate

Base Information

Chemical Name:1-Benzyl-5-oxopyrrolidin-2-yl acetate
CAS No.:88461-15-8
Molecular Formula:C13H15NO3
Molecular Weight:233.267
Hs Code.:
DSSTox Substance ID:DTXSID60525062
Nikkaji Number:J2.756.521B

Synonyms:88461-15-8;1-Benzyl-5-oxopyrrolidin-2-yl acetate;DTXSID60525062

Suppliers and Price of 1-Benzyl-5-oxopyrrolidin-2-yl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-Benzyl-5-oxopyrrolidin-2-yl acetate

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:233.10519334
Heavy Atom Count:17
Complexity:297

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OC1CCC(=O)N1CC2=CC=CC=C2

Technology Process of 1-Benzyl-5-oxopyrrolidin-2-yl acetate

There total 1 articles about 1-Benzyl-5-oxopyrrolidin-2-yl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2142-06-5
1-(phenylmethyl)-2,5-pyrrolidinedione

: 88461-15-8
1-benzyl-5-oxopyrrolidin-2-yl acetate

Guidance literature:: Multi-step reaction with 2 steps

1: NaBH₄/H⁽¹⁺⁾ / 0 °C

2: 94 percent / acetic acid / 20 h / Ambient temperature

With sodium tetrahydroborate; hydrogen cation; In acetic acid;

Reference yield: 90.0%

: 120-72-9
indole

: 88461-15-8
1-benzyl-5-oxopyrrolidin-2-yl acetate

: 1190881-51-6
(R)-1-benzyl-5-(1H-indol-3-yl)pyrrolidin-2-one

Guidance literature:: With chloro-trimethyl-silane; 1-((1R,2R)-2-((E)-5-tert-butyl-2-hydroxy-3-(triethylsilyl)benzylideneamino)cyclohexyl)-3-((S)-1-oxo-3-phenyl-1-((R)-2-phenylpyrrolidin-1-yl)propan-2-yl)thiourea; water; In tert-butyl methyl ether; at -78 - -30 ℃; enantioselective reaction; Inert atmosphere;
DOI:10.1002/anie.200902420

Reference yield: 86.0%

: 16096-32-5,261352-49-2
4-methyl-1H-indole

: 88461-15-8
1-benzyl-5-oxopyrrolidin-2-yl acetate

: 1190881-53-8
(R)-1-benzyl-5-(4-methyl-1H-indol-3-yl)pyrrolidin-2-one

Guidance literature:: With chloro-trimethyl-silane; 1-((1R,2R)-2-((E)-5-tert-butyl-2-hydroxy-3-(triethylsilyl)benzylideneamino)cyclohexyl)-3-((S)-1-oxo-3-phenyl-1-((R)-2-phenylpyrrolidin-1-yl)propan-2-yl)thiourea; water; In tert-butyl methyl ether; at -78 - -30 ℃; enantioselective reaction; Inert atmosphere;
DOI:10.1002/anie.200902420