5-Iodo-8-methylquinoline

Base Information

Chemical Name:5-Iodo-8-methylquinoline
CAS No.:88474-17-3
Molecular Formula:C10H8IN
Molecular Weight:269.08200
Hs Code.:
DSSTox Substance ID:DTXSID60524671
Nikkaji Number:J2.629.381B
Wikidata:Q82391704
Mol file:88474-17-3.mol

Synonyms:5-Iodo-8-methylquinoline;88474-17-3;Quinoline, 5-iodo-8-methyl-;SCHEMBL6019580;DTXSID60524671;F75447

Suppliers and Price of 5-Iodo-8-methylquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemcia Scientific
5-Iodo-8-methyl-quinoline 95%
5 G
$ 825.00

Total 7 raw suppliers

Chemical Property of 5-Iodo-8-methylquinoline

Chemical Property:

Melting Point:51.5-52 °C(Solv: ethanol (64-17-5))
Boiling Point:332.5±22.0 °C(Predicted)
PKA:4.03±0.29(Predicted)
PSA：12.89000
Density:1.734±0.06 g/cm3(Predicted)
LogP:3.14780
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:268.97015
Heavy Atom Count:12
Complexity:160

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-Iodo-8-methyl-quinoline 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C(=C(C=C1)I)C=CC=N2

Technology Process of 5-Iodo-8-methylquinoline

There total 3 articles about 5-Iodo-8-methylquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 611-32-5
8-methylquinoline

: 88474-17-3
5-iodo-8-methylquinoline

Guidance literature:: With iodine; silver sulfate; In sulfuric acid; 1.)20 deg C, 45 h 2.)90-95 deg C;
DOI:10.1007/BF00505763

Reference yield:

: 83863-33-6
5-iodo-o-toluidine

: 56-81-5,25618-55-7,64333-26-2,8013-25-0
glycerol

: 88474-17-3
5-iodo-8-methylquinoline

Guidance literature:: With sulfuric acid; sodium iodide; In water; at 140 - 145 ℃; for 4h; Inert atmosphere; Schlenk technique;
DOI:10.1021/jo5008515

Reference yield:

: 78941-95-4
5-chloro-8-methylquinoline

: 88474-17-3
5-iodo-8-methylquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 5.3 percent Chromat_. / Cl₂ / silver sulfate / H₂SO₄ / 1.)8 h 2.)r.t., 20 h

2: 91 percent / I₂ / silver sulfate / H₂SO₄ / 1.)20 deg C, 45 h 2.)90-95 deg C

With iodine; chlorine; silver sulfate; In sulfuric acid;
DOI:10.1007/BF00505763