(5-Benzyl-2-phenyl-1,3-dioxan-4-yl)methanol

Base Information

Chemical Name:(5-Benzyl-2-phenyl-1,3-dioxan-4-yl)methanol
CAS No.:88481-72-5
Molecular Formula:C18H20O3
Molecular Weight:284.355
Hs Code.:
DSSTox Substance ID:DTXSID40526678

Synonyms:(5-Benzyl-2-phenyl-1,3-dioxan-4-yl)methanol;88481-72-5;DTXSID40526678

Suppliers and Price of (5-Benzyl-2-phenyl-1,3-dioxan-4-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of (5-Benzyl-2-phenyl-1,3-dioxan-4-yl)methanol

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:284.14124450
Heavy Atom Count:21
Complexity:295

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(OC(O1)C2=CC=CC=C2)CO)CC3=CC=CC=C3

Technology Process of (5-Benzyl-2-phenyl-1,3-dioxan-4-yl)methanol

There total 4 articles about (5-Benzyl-2-phenyl-1,3-dioxan-4-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 100-52-7
benzaldehyde

: 88481-71-4
(2S,3S)-3-benzyl-1,2,4-butanetriol

: 88481-72-5
(4S,5S)-5-Benzyl-4-hydroxymethyl-2-phenyl-1,3-dioxan

Guidance literature:: With zinc(II) chloride; for 48h; Ambient temperature;

Reference yield:

: 88481-70-3
(2S,3R)-3-Benzyl-2-(1-methoxy-1-methylethoxy)-1,4-butandiol

: 88481-72-5
(4S,5S)-5-Benzyl-4-hydroxymethyl-2-phenyl-1,3-dioxan

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / Dowex 50 W / tetrahydrofuran; H₂O / 12 h / 50 °C

2: 62 percent / anh. ZnCl₂ / 48 h / Ambient temperature

With Dowex 50 W; zinc(II) chloride; In tetrahydrofuran; water;

Reference yield:

: 73828-17-8
(2S,3R)-3-Benzyl-2-hydroxybernsteinsaeure-diethylester

: 88481-72-5
(4S,5S)-5-Benzyl-4-hydroxymethyl-2-phenyl-1,3-dioxan

Guidance literature:: Multi-step reaction with 4 steps

1: 14.8 g / picric acid / CH₂Cl₂ / 15 h / Ambient temperature

2: 11.2 g / LAH / tetrahydrofuran / 15 h / Ambient temperature; 1) THF, 15h, r. t., 2) H₂O, 30 min, ice-cooled

3: 92 percent / Dowex 50 W / tetrahydrofuran; H₂O / 12 h / 50 °C

4: 62 percent / anh. ZnCl₂ / 48 h / Ambient temperature

With lithium aluminium tetrahydride; Dowex 50 W; 2,4,6-Trinitrophenol; zinc(II) chloride; In tetrahydrofuran; dichloromethane; water;