N-(2-Hydroxyphenyl)-2-pyridinecarboxamide

Base Information

Chemical Name:N-(2-Hydroxyphenyl)-2-pyridinecarboxamide
CAS No.:88530-99-8
Molecular Formula:C12H10N2O2
Molecular Weight:214.224
Hs Code.:
DSSTox Substance ID:DTXSID60357067
Nikkaji Number:J1.785.201I
Wikidata:Q27216231

Synonyms:88530-99-8;N-(2-Hydroxyphenyl)-2-pyridinecarboxamide;N-(2-hydroxyphenyl)picolinamide;N-(2-hydroxyphenyl)pyridine-2-carboxamide;BAS 00134377;WAY-296712;Oprea1_150731;Oprea1_753684;SCHEMBL5711050;DTXSID60357067;CHEBI:125618;HMS1679K17;EX-A6522;AKOS000525784;SR-01000358088;SR-01000358088-1;BRD-K69471245-001-02-7;Q27216231

Suppliers and Price of N-(2-Hydroxyphenyl)-2-pyridinecarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N-(2-Hydroxyphenyl)-2-pyridinecarboxamide

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:214.074227566
Heavy Atom Count:16
Complexity:245

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)NC(=O)C2=CC=CC=N2)O

Technology Process of N-(2-Hydroxyphenyl)-2-pyridinecarboxamide

There total 5 articles about N-(2-Hydroxyphenyl)-2-pyridinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 95-55-6
2-amino-phenol

: 88530-99-8
pyridine-2-carboxylic acid (2-hydroxy-phenyl)-amide

Guidance literature:: 2-amino-phenol; With trimethylaluminum chloride; In toluene; at 0 - 20 ℃;

hydroxymethyl JandaJel^TM resin-bound 2-pyridyl ester; In toluene; for 24h; Further stages.; Heating;
DOI:10.1016/j.tetlet.2003.10.168

Reference yield:

: 29745-44-6
pyridine-2-carbonyl chloride

: 95-55-6
2-amino-phenol

: 88530-99-8
pyridine-2-carboxylic acid (2-hydroxy-phenyl)-amide

Guidance literature:: With triethylamine; In tetrahydrofuran; for 5h; Heating;
DOI:10.1002/1099-0682(200203)2002:4<859::AID-EJIC859>3.0.CO;2-Z

Reference yield:

: 109-04-6
2-bromo-pyridine

: 201230-82-2
carbon monoxide

: 95-55-6
2-amino-phenol

: 88530-99-8
pyridine-2-carboxylic acid (2-hydroxy-phenyl)-amide

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; bis-triphenylphosphine-palladium(II) chloride; triphenylphosphine; In toluene; at 120 ℃; for 1.25h; under 4654.3 Torr;
DOI:10.1021/jo00036a025