tert-Butyl (2-oxo-2-(piperidin-1-yl)ethyl)carbamate

Base Information

Chemical Name:tert-Butyl (2-oxo-2-(piperidin-1-yl)ethyl)carbamate
CAS No.:88621-47-0
Molecular Formula:C12H22N2O3
Molecular Weight:242.318
Hs Code.:
DSSTox Substance ID:DTXSID40557088
Nikkaji Number:J1.954.029D
Wikidata:Q82438848

Synonyms:88621-47-0;tert-Butyl (2-oxo-2-(piperidin-1-yl)ethyl)carbamate;N-[2-oxo-2-(1-piperidinyl)ethyl]carbamic acid tert-butyl ester;tert-Butyl [2-oxo-2-(piperidin-1-yl)ethyl]carbamate;SCHEMBL4472678;DTXSID40557088;UUOVAOBRQYWLNB-UHFFFAOYSA-N;(2-oxo-2-piperidin-1-yl-ethyl)-carbamic acid tert-butyl ester;A822309;tert-butyl N-[2-oxo-2-(1-piperidyl)ethyl]carbamate;(2-Oxo-2-piperidin-1-yl-ethyl)carbamic acid tert-butyl ester

Suppliers and Price of tert-Butyl (2-oxo-2-(piperidin-1-yl)ethyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of tert-Butyl (2-oxo-2-(piperidin-1-yl)ethyl)carbamate

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:242.16304257
Heavy Atom Count:17
Complexity:278

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCC(=O)N1CCCCC1

Technology Process of tert-Butyl (2-oxo-2-(piperidin-1-yl)ethyl)carbamate

There total 3 articles about tert-Butyl (2-oxo-2-(piperidin-1-yl)ethyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 110-89-4
piperidine

: 31954-27-5
N-(tert-butoxycarbonyl)glycine methyl ester

: 88621-47-0
N-<((tert-butoxycarbonyl)amino)acetyl>piperidine

Guidance literature:: In methanol; at 80 ℃; for 4h; Inert atmosphere;
DOI:10.1002/adsc.202100964

Reference yield:

: 110-89-4
piperidine

: 36016-38-3
tert-Butyl N-hydroxycarbamate

: 40052-13-9
mono-tert-butyl malonate

: 88621-47-0
N-<((tert-butoxycarbonyl)amino)acetyl>piperidine

Guidance literature:: piperidine; mono-tert-butyl malonate; With dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 12h; Cooling with ice;

With trifluoroacetic acid; In dichloromethane; for 1h; Cooling with ice;

tert-Butyl N-hydroxycarbamate; With 1,1'-carbonyldiimidazole; In dichloromethane; at 0 - 20 ℃; for 0.5h;