Benzeneacetic acid, a-methyl-, butyl ester

Base Information

• Chemical Name: Benzeneacetic acid, a-methyl-, butyl ester
• CAS No.: 88641-61-6
• Molecular Formula: C13H18O2
• Molecular Weight: 206.285
• Mol file: 88641-61-6.mol

Synonyms:

Chemical Property of Benzeneacetic acid, a-methyl-, butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzeneacetic acid, a-methyl-, butyl ester

There total 10 articles about Benzeneacetic acid, a-methyl-, butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

hydratropic acid (492-37-5,2328-24-7) + butan-1-ol (71-36-3) → 2-phenylpropionic butyl ester (88641-61-6)

Guidance literature:

With sulfuric acid; In toluene; at 120 ℃; Dean-Stark;

DOI:10.1002/cbic.201402685

Reference yield: 79.3%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + carbon monoxide (201230-82-2) + butan-1-ol (71-36-3) → 2-phenylpropionic butyl ester (88641-61-6)

Guidance literature:

With 0.17percent Pd-P-OP/LSI-600 catalyst; In toluene; at 80 ℃; for 3.5h; under 22502.3 Torr; Autoclave;

DOI:10.1039/c3cy00842h

Reference yield: 50.0%

lithium isopropenolate (67863-40-5) + methyl phenyl ketene (3156-07-8) → 2-phenylpropionic acid methyl ester (31508-44-8) + 2-phenylpropionic butyl ester (88641-61-6) + 1-methylvinyl 2-phenylpropanoate (117760-34-6)

Guidance literature:

In tetrahydrofuran; at -78 - 25 ℃; for 2h; Yield given;

DOI:10.1021/jo00298a047

upstream raw materials:

n-butyllithium

lithium isopropenolate

methyl phenyl ketene

n-butyl formate

Downstream raw materials:

2-(3-chlorosulfonyl-phenyl)propionic butyl ester

2-(4-chlorosulfonyl-phenyl)propionic butyl ester