Hydratropic acid, p-(2-pyridinylamino)-

Base Information

Chemical Name:Hydratropic acid, p-(2-pyridinylamino)-
CAS No.:76302-29-9
Molecular Formula:C14H14N2O2
Molecular Weight:242.277
Hs Code.:
UNII:73YDE13QG9
DSSTox Substance ID:DTXSID80997661
Nikkaji Number:J59.871B
Wikidata:Q27266216
ChEMBL ID:CHEMBL72565

Synonyms:76302-29-9;AD-1491;Hydratropic acid, p-(2-pyridinylamino)-;p-(2-Pyridinylamino)hydratropic acid;BRN 6211437;2-(4-(2'-Pyridylamino)phenyl)propionic acid;UNII-73YDE13QG9;73YDE13QG9;2-(4-(2-Pyridylamino)phenyl)propionic acid;Benzeneacetic acid, alpha-methyl-4-(2-pyridinylamino)-;2-[4-(pyridin-2-ylamino)phenyl]propanoic acid;CHEMBL72565;SCHEMBL9838994;DTXSID80997661;AD 1491;LS-76357;2-{4-[(Pyridin-2-yl)amino]phenyl}propanoic acid;Q27266216;BENZENEACETIC ACID, .ALPHA.-METHYL-4-(2-PYRIDINYLAMINO)-

Suppliers and Price of Hydratropic acid, p-(2-pyridinylamino)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Hydratropic acid, p-(2-pyridinylamino)-

Chemical Property:

Vapor Pressure:5.04E-08mmHg at 25°C
Boiling Point:426.2°Cat760mmHg
Flash Point:211.6°C
Density:1.252g/cm³
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:242.105527694
Heavy Atom Count:18
Complexity:275

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=C(C=C1)NC2=CC=CC=N2)C(=O)O

Technology Process of Hydratropic acid, p-(2-pyridinylamino)-

There total 7 articles about Hydratropic acid, p-(2-pyridinylamino)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 83528-18-1
2-[4-(Pyridin-2-ylamino)-phenyl]-propionic acid methyl ester

: 76302-29-9
2-[4-(2'-pyridylamino)phenyl]propionic acid

Guidance literature:: With sodium hydroxide; In methanol; for 1h; Ambient temperature;
DOI:10.1021/jm00356a019

Reference yield: 72.0%

: 109-09-1
2-chloropyridine

: 39718-97-3
methyl 2-(4-aminophenyl)propanoate

: 76302-29-9
2-[4-(2'-pyridylamino)phenyl]propionic acid

Guidance literature:: With sodium hydroxide; In methanol;

Reference yield:

: 100-00-5
4-chlorobenzonitrile

: 76302-29-9
2-[4-(2'-pyridylamino)phenyl]propionic acid

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) NaH / 1.) DMF, 50 deg C, 20 min, 2.) DMF, 100 deg C, 2 h

2: NaOH / dimethylformamide; methanol; H₂O / 1 h / 50 °C

3: concd. H₂SO₄ / 3 h / Heating

4: 94 percent / H₂ / 5percent Pd/C / ethanol / 760 Torr

5: 160 - 170 °C

6: 78 percent / 10percent NaOH / methanol / 1 h / Ambient temperature

With sodium hydroxide; sulfuric acid; hydrogen; sodium hydride; palladium on activated charcoal; In methanol; ethanol; water; N,N-dimethyl-formamide;
DOI:10.1021/jm00356a019