N-Benzylidene-N'-(2-nitro-phenyl)-hydrazine

Base Information

• Chemical Name: N-Benzylidene-N'-(2-nitro-phenyl)-hydrazine
• CAS No.: 5335-90-0
• Molecular Formula: C13H11N3O2
• Molecular Weight: 241.249
• NSC Number: 999
• DSSTox Substance ID: DTXSID40416262
• ChEMBL ID: CHEMBL3214404
• Mol file: 5335-90-0.mol

Synonyms:N-Benzylidene-N'-(2-nitro-phenyl)-hydrazine;Benzaldehyde, (2-nitrophenyl)hydrazone;5335-90-0;NSC999;MLS001207249;CHEMBL3214404;DTXSID40416262;NSC-999;STK049411;AKOS000483235;1-benzylidene-2-(2-nitrophenyl)hydrazine;SMR000514597;(1E)-1-benzylidene-2-(2-nitrophenyl)hydrazine;AB00078526-01

Chemical Property of N-Benzylidene-N'-(2-nitro-phenyl)-hydrazine

Chemical Property:

• Vapor Pressure: 1.47E-06mmHg at 25°C
• Boiling Point: 398.5°Cat760mmHg
• Flash Point: 194.8°C
• Density: 1.2g/cm³
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 241.085126602
• Heavy Atom Count: 18
• Complexity: 295

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C=NNC2=CC=CC=C2[N+](=O)[O-]
• Isomeric SMILES: C1=CC=C(C=C1)/C=N/NC2=CC=CC=C2[N+](=O)[O-]

Technology Process of N-Benzylidene-N'-(2-nitro-phenyl)-hydrazine

There total 7 articles about N-Benzylidene-N'-(2-nitro-phenyl)-hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.7%

1,2'-diphenyl-3,5-dioxo-1,2,3,5-tetrahydrospiropyrazole-4,3'-oxirane (1296783-86-2) + (2-nitrophenyl)hydrazine (3034-19-3) → 4-[2-(2-nitrophenyl)hydrazinylidene]-1-phenylpyrazolidine-3,5-dione (898660-12-3) + benzaldehyde 2-nitrophenylhydrazone (5335-90-0)

Guidance literature:

In ethanol; for 4h; Reflux;

DOI:10.1007/s10593-011-0671-x

Reference yield:

benzaldehyde (100-52-7) + (2-nitrophenyl)hydrazine (3034-19-3) → benzaldehyde 2-nitrophenylhydrazone (5335-90-0)

Guidance literature:

With ethanol;

Reference yield:

(2-nitro-phenylhydrazono)-phenyl-acetonitrile (69852-67-1) → benzaldehyde 2-nitrophenylhydrazone (5335-90-0)

Guidance literature:

Multi-step reaction with 2 steps

1: alcoholic KOH-solution

2: beim Erhitzen ueber den Schmelzpunkt

With potassium hydroxide;

upstream raw materials:

((Z)-2-nitro-phenylhydrazono)-phenyl-acetic acid

benzaldehyde

(2-nitrophenyl)hydrazine

(2-nitro-phenylhydrazono)-phenyl-acetonitrile

Downstream raw materials:

1-o-Nitrophenyl-3,5-diphenylformazan

N'-(4-bromo-2-nitro-phenyl)-benzohydrazonoyl bromide

2-phenyl-1H-benzoimidazole

benzaldehyde-(2-amino-phenylhydrazone)