1296783-86-2Relevant academic research and scientific papers
Green synthetic investigation and spectral characterization of some spiro pyrazolidine-based heterocycles with potential biological activity
El-Ossaily, Yasser A.,Metwally, Saoud A.,Al-Muailkel, Nayef S.,Fawzy, Ahmed,Ali, Hazim M.,Naffea, Yousra A.
, p. 1729 - 1736 (2020/01/25)
A green, rapid, and efficient methodology is developed for the synthesis of 1-phenyl-3,5-pyrazolidinedione (3) by the reaction of malonic acid with phenyl hydrazine in the presence of phosphorous oxychloride under solvent-free conditions. The later compou
