N-(3-Aminopropyl)methacrylamide hydrochloride

Base Information

• Chemical Name: N-(3-Aminopropyl)methacrylamide hydrochloride
• CAS No.: 72607-53-5
• Molecular Formula: C₇H₁₄N₂O*ClH
• Molecular Weight: 178.662
• Hs Code.: 29241990
• European Community (EC) Number: 662-677-4
• DSSTox Substance ID: DTXSID3072581
• Mol file: 72607-53-5.mol

Synonyms:72607-53-5;N-(3-AMINOPROPYL)METHACRYLAMIDE HYDROCHLORIDE;2-Propenamide, N-(3-aminopropyl)-2-methyl-, monohydrochloride;N-(3-AMINOPROPYL) METHACRYLAMIDE hydrochloride;N-(3-AMINOPROPYL) METHACRYLAMIDE;MFCD00078257;N-(3-Aminopropyl)methacrylamide, HCl;N-(3-aminopropyl)-2-methylprop-2-enamide;hydrochloride;N-(3-AMINOPROPYL)METHACRYLAMIDE HCL;2-Propenamide, N-(3-aminopropyl)-2-methyl-, hydrochloride (1:1);APMA;N-(3-Aminopropyl)methacrylamide hydrochloride,>98%;N-(3-aminopropyl)-2-methylprop-2-enamide hydrochloride;C7H14N2O.ClH;SCHEMBL82715;DTXSID3072581;C7-H14-N2-O.Cl-H;XHIRWEVPYCTARV-UHFFFAOYSA-N;BCP19654;AKOS008901248;CS-W002334;GS-4222;3-methacrylamidopropylamine hydrochloride;AM807272;SY017925;N-(3-Amnopropyl)methacrylamde hydrochlorde;N(3-aminopropyl)methacrylamide hydrochloride;FT-0600293;n-(3-aminopropyl)-methacrylamide hydrochloride;A866234;J-522992;2-Propenamide, N-(3-aminopropyl)-2-methyl-, hydrochloride;N-(3-Aminopropyl)methacrylamide hydrochloride, contains <=1,000 ppm MEHQ as stabilizer, 98% (HPLC)

Chemical Property of N-(3-Aminopropyl)methacrylamide hydrochloride

Chemical Property:

• Vapor Pressure: 0.000565mmHg at 25°C
• Melting Point: 123-128°C
• Boiling Point: 311.4 °C at 760 mmHg
• Flash Point: 142.1 °C
• PSA: 55.12000
• LogP: 1.92070
• Storage Temp.: 2-8°C
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 178.0872908
• Heavy Atom Count: 11
• Complexity: 132

Purity/Quality:

99% ^*data from raw suppliers

N-(3-Aminopropyl)methacrylamide hydrochloride 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=C)C(=O)NCCCN.Cl
• Uses: APMA can be used in the preparation of copolymers and cross-linked miscellas for gene delivery, drug delivery and diagnostics applications.

Technology Process of N-(3-Aminopropyl)methacrylamide hydrochloride

There total 2 articles about N-(3-Aminopropyl)methacrylamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

tert-butyl (3-methacrylamidopropyl)carbamate (219739-79-4) → N-(3-aminopropyl)methacrylamide hydrochloride (72607-53-5)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; methanol; at 20 ℃; for 16h;

Reference yield:

N,N-Dimethylacrylamide (2680-03-7,68761-83-1) + 2-mercaptoethylamine hydrochloride (156-57-0) → hydroxy-ethyl acrylate (13331-72-1) + N-(3-aminopropyl)methacrylamide hydrochloride (72607-53-5)

Guidance literature:

In propan-1-ol;

Reference yield: 92.0%

benzoylmercaptoacetylglycylglycylglycine (103725-47-9) + N-(3-aminopropyl)methacrylamide hydrochloride (72607-53-5) → C22H29N5O6S

Guidance literature:

benzoylmercaptoacetylglycylglycylglycine; With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; for 0.166667h;

N-(3-aminopropyl)methacrylamide hydrochloride; With 10H-phenothiazine; In N,N-dimethyl-formamide; for 32h;

upstream raw materials:

N,N-Dimethylacrylamide

2-mercaptoethylamine hydrochloride

tert-butyl (3-methacrylamidopropyl)carbamate

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