2(3H)-Oxazolone, 4-(4-fluorophenyl)-3-(phenylmethyl)-5-(2-(4-phenyl-1-piperazinyl)ethyl)-

Base Information

Chemical Name:2(3H)-Oxazolone, 4-(4-fluorophenyl)-3-(phenylmethyl)-5-(2-(4-phenyl-1-piperazinyl)ethyl)-
CAS No.:52867-96-6
Molecular Formula:C28H28FN3O2
Molecular Weight:457.5392
Hs Code.:
DSSTox Substance ID:DTXSID90200895
Wikidata:Q83074071
ChEMBL ID:CHEMBL306650
Mol file:52867-96-6.mol

Synonyms:BRN 1189763;2(3H)-Oxazolone, 4-(4-fluorophenyl)-3-(phenylmethyl)-5-(2-(4-phenyl-1-piperazinyl)ethyl)-;4-(4-Fluorophenyl)-3-(phenylmethyl)-5-(2-(4-phenyl-1-piperazinyl)ethyl)-2(3H)-oxazolone;52867-96-6;CHEMBL306650;C28H28FN3O2;DTXSID90200895;C28-H28-F-N3-O2;LS-100832

Suppliers and Price of 2(3H)-Oxazolone, 4-(4-fluorophenyl)-3-(phenylmethyl)-5-(2-(4-phenyl-1-piperazinyl)ethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2(3H)-Oxazolone, 4-(4-fluorophenyl)-3-(phenylmethyl)-5-(2-(4-phenyl-1-piperazinyl)ethyl)-

Chemical Property:

Vapor Pressure:1.32E-14mmHg at 25°C
Boiling Point:605.4°Cat760mmHg
Flash Point:319.9°C
Density:1.237g/cm³
XLogP3:5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:457.21655531
Heavy Atom Count:34
Complexity:700

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CCC2=C(N(C(=O)O2)CC3=CC=CC=C3)C4=CC=C(C=C4)F)C5=CC=CC=C5

Technology Process of 2(3H)-Oxazolone, 4-(4-fluorophenyl)-3-(phenylmethyl)-5-(2-(4-phenyl-1-piperazinyl)ethyl)-

There total 2 articles about 2(3H)-Oxazolone, 4-(4-fluorophenyl)-3-(phenylmethyl)-5-(2-(4-phenyl-1-piperazinyl)ethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 75-44-5
phosgene

: 100-46-9
benzylamine

: 51037-47-9
1-(4-fluorophenyl)-2-hydroxy-4-(4-phenyl-1-piperazinyl)-1-butanone

: 52867-96-6
3-benzyl-4-(4-fluoro-phenyl)-5-[2-(4-phenyl-piperazin-1-yl)-ethyl]-3H-oxazol-2-one

Guidance literature:: With triethylamine; Yield given. Multistep reaction; 1) CHCl₃, 0 deg C, 2 h, 2) 0 deg C to room temperature;
DOI:10.1021/jm00130a003