1-BroMo-4-(t-butyldiMethylsilyloxy)butane

Base Information

• Chemical Name: 1-BroMo-4-(t-butyldiMethylsilyloxy)butane
• CAS No.: 89043-32-3
• Molecular Formula: C10H23BrOSi
• Molecular Weight: 267.282
• Mol file: 89043-32-3.mol

Synonyms:1-bromo-4-(tert-butyldimethylsiloxy)butane;4-bromo-1-(tert-butyldimethylsiloxy)butane;Silane,(4-bromobutoxy)(1,1-dimethylethyl)dimethyl;4-tert-butyldimethylsilyloxy-1-bromobutane;4-bromo-1-(tert-butyldimethylsilyloxy)butane;1-Bromo-4-(t-butyldimethylsilyloxy)butane;(4-bromobutoxy)(tert-butyl)dimethylsilane;

Chemical Property of 1-BroMo-4-(t-butyldiMethylsilyloxy)butane

Chemical Property:

• Boiling Point: 250.4±13.0 °C(Predicted)
• PSA: 9.23000
• Density: 1.073±0.06 g/cm3(Predicted)
• LogP: 4.18330
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

1-Bromo-4-(t-butyldimethylsilyloxy)butane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-BroMo-4-(t-butyldiMethylsilyloxy)butane

There total 5 articles about 1-BroMo-4-(t-butyldiMethylsilyloxy)butane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-Bromo-1-butanol (33036-62-3) + tert-butyldimethylsilyl chloride (18162-48-6) → (4-bromobutoxy)-tert-butyldimethylsilane (89043-32-3)

Guidance literature:

With 1H-imidazole; In dichloromethane; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1039/c5ob01636c

Reference yield: 90.0%

4-tert-butyldimethylsilyloxybutan-1-ol (87184-99-4) → (4-bromobutoxy)-tert-butyldimethylsilane (89043-32-3)

Guidance literature:

With tetrabutylammomium bromide; (chloro-phenylthio-methylene)dimethylammonium chloride; In dichloromethane; at 20 ℃;

DOI:10.1016/S0040-4039(00)00940-0

Reference yield: 80.0%

4-Bromo-1-butanol (33036-62-3) + tert-butylchlorodiphenylsilane (58479-61-1) → (4-bromobutoxy)-tert-butyldimethylsilane (89043-32-3)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 20 ℃;

DOI:10.1021/ja036521e

upstream raw materials:

4-Bromo-1-butanol

tert-butyldimethylsilyl chloride

4-tert-butyldimethylsilyloxybutan-1-ol

tert-butylchlorodiphenylsilane

Downstream raw materials:

4-<1-phenylsulfonyl-5<<(1,1-dimethylethyl)dimethylsilyl>oxy>-pentyl>-2(5H)-furanone

2-[4-(tert-butyl-dimethyl-silanyloxy)-butyl]-cyclohex-2-enone

(4-hydroxybutyl)-triphenylphosphonium bromide

(6R)-6-O-benzyl-1-O-(tert-butyldimethylsilyl)-1,6-heptanediol