3-(4-Chlorophenyl)-1-methyl-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole

Base Information

Chemical Name:3-(4-Chlorophenyl)-1-methyl-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole
CAS No.:89144-89-8
Molecular Formula:C14H13ClN2S
Molecular Weight:276.78400
Hs Code.:
DSSTox Substance ID:DTXSID30524082

Synonyms:89144-89-8;SCHEMBL7200428;DTXSID30524082;3-(4-Chlorophenyl)-1-methyl-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole

Suppliers and Price of 3-(4-Chlorophenyl)-1-methyl-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 3-(4-Chlorophenyl)-1-methyl-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole

Chemical Property:

PSA：43.84000
LogP:3.55590
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:276.0487973
Heavy Atom Count:18
Complexity:326

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(CC(=N1)C2=CC=C(C=C2)Cl)C3=CC=CS3

Technology Process of 3-(4-Chlorophenyl)-1-methyl-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole

There total 4 articles about 3-(4-Chlorophenyl)-1-methyl-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 6028-91-7
1-(4-chlorophenyl)-3-(thiophen-2-yl)prop-2-en-1-one

: 60-34-4
methylhydrazine

: 89144-89-8
1-methyl-3-(4-chlorophenyl)-5-(2-thienyl)-pyrazoline

Guidance literature:: With potassium hydroxide; In ethanol; for 3h; Heating;
DOI:10.1021/je00036a038

Reference yield:

: 98-03-3
thiophene-2-carbaldehyde

: 89144-89-8
1-methyl-3-(4-chlorophenyl)-5-(2-thienyl)-pyrazoline

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaOH / 2 h

2: 82 percent / KOH / ethanol / 3 h / Heating

With potassium hydroxide; sodium hydroxide; In ethanol;
DOI:10.1021/je00036a038

Reference yield:

: 99-91-2
para-chloroacetophenone

: 89144-89-8
1-methyl-3-(4-chlorophenyl)-5-(2-thienyl)-pyrazoline

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaOH / 2 h

2: 82 percent / KOH / ethanol / 3 h / Heating

With potassium hydroxide; sodium hydroxide; In ethanol;
DOI:10.1021/je00036a038