Ethyl 2-(2-oxo-2-phenylethyl)pyridine-1(2H)-carboxylate

Base Information

Chemical Name:Ethyl 2-(2-oxo-2-phenylethyl)pyridine-1(2H)-carboxylate
CAS No.:89318-20-7
Molecular Formula:C₁₆H₁₇NO₃
Molecular Weight:271.316
Hs Code.:
DSSTox Substance ID:DTXSID00519622

Synonyms:89318-20-7;DTXSID00519622;Ethyl 2-(2-oxo-2-phenylethyl)pyridine-1(2H)-carboxylate

Suppliers and Price of Ethyl 2-(2-oxo-2-phenylethyl)pyridine-1(2H)-carboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Ethyl 2-(2-oxo-2-phenylethyl)pyridine-1(2H)-carboxylate

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:271.12084340
Heavy Atom Count:20
Complexity:408

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)N1C=CC=CC1CC(=O)C2=CC=CC=C2

Technology Process of Ethyl 2-(2-oxo-2-phenylethyl)pyridine-1(2H)-carboxylate

There total 5 articles about Ethyl 2-(2-oxo-2-phenylethyl)pyridine-1(2H)-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 13735-81-4
1-styrenyloxytrimethylsilane

: 63755-30-6
N-ethoxycarbonylpyridinium chloride

: 89318-18-3
4-(2-Oxo-2-phenyl-ethyl)-4H-pyridine-1-carboxylic acid ethyl ester

: 89318-20-7
2-(2-Oxo-2-phenyl-ethyl)-2H-pyridine-1-carboxylic acid ethyl ester

Guidance literature:: In dichloromethane; at 0 ℃; for 5h; using t-butyldimethylsilyl enol ether;
DOI:10.1016/S0040-4039(00)88414-2

Reference yield: 11.0%

: 66324-10-5
tert-butyldimethyl(1-phenylvinyloxy)silane

: 63755-30-6
N-ethoxycarbonylpyridinium chloride

: 89318-18-3
4-(2-Oxo-2-phenyl-ethyl)-4H-pyridine-1-carboxylic acid ethyl ester

: 89318-20-7
2-(2-Oxo-2-phenyl-ethyl)-2H-pyridine-1-carboxylic acid ethyl ester

: 89318-22-9
4-[(E)-2-(tert-Butyl-dimethyl-silanyloxy)-2-phenyl-vinyl]-4H-pyridine-1-carboxylic acid ethyl ester

Guidance literature:: for 8h;
DOI:10.1016/S0040-4039(00)88414-2

Reference yield:

: 110-86-1
pyridine

: 89318-20-7
2-(2-Oxo-2-phenyl-ethyl)-2H-pyridine-1-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

2: 21 percent / 5 h / using t-butyldimethylsilyl enol ether

DOI:10.1016/S0040-4039(00)88414-2