Tosylate of Tetraethylene glycol monobenzyl ether

Base Information

Chemical Name:Tosylate of Tetraethylene glycol monobenzyl ether
CAS No.:89346-82-7
Molecular Formula:C22H30O7S
Molecular Weight:438.542
Hs Code.:
Mol file:89346-82-7.mol

Synonyms:2,5,8,11-Tetraoxatridecan-13-ol,1-phenyl-,4-methylbenzenesulfonate;tetraethylene glycol monobenzyl ether tosylate;1-phenyl-2,5,8,11-tetraoxatridecan-13-yl 4-methylbenzenesulfonate;13-phenyl-3,6,9,12-tetraoxatridecan-1-yl p-toluenesulfonate;

Suppliers and Price of Tosylate of Tetraethylene glycol monobenzyl ether

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Toluene-4-sulfonic acid 2-{2-[2-(2-benzyloxyethoxy)-ethoxy]-ethoxy}-ethyl ester 95%
5g
$ 1733.00

Activate Scientific
1-Phenyl-2,5,8,11-tetraoxatridecan-13-yl4-methylbenzenesulfonate 97%
250 mg
$ 130.00

Activate Scientific
1-Phenyl-2,5,8,11-tetraoxatridecan-13-yl4-methylbenzenesulfonate 97%
5 g
$ 1042.00

Absolute Chiral
1-phenyl-2,5,8,11-tetraoxatridecan-13-yl4-methylbenzenesulfonate 95%
1 g
$ 298.00

Total 11 raw suppliers

Chemical Property of Tosylate of Tetraethylene glycol monobenzyl ether

Chemical Property:

PSA：119.90000
LogP:3.56780

Purity/Quality:

98% ^*data from raw suppliers

Toluene-4-sulfonic acid 2-{2-[2-(2-benzyloxyethoxy)-ethoxy]-ethoxy}-ethyl ester 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Benzyl-PEG4-Ots is a PEG-based PROTAC linker that can be used to synthesize PROTACs.

Technology Process of Tosylate of Tetraethylene glycol monobenzyl ether

There total 11 articles about Tosylate of Tetraethylene glycol monobenzyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 86259-87-2,1201808-31-2
1-phenyl-2,5,8,11-tetraoxatridecan-13-ol

: 98-59-9
p-toluenesulfonyl chloride

: 89346-82-7
2-<2-<2-<2-(benzyloxy)ethoxy>ethoxy>ethoxy>ethyl 4-methylbenzenesulfonate

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 12h;

Reference yield: 99.6%

: 111-77-3,95507-80-5
2-(2-methoxyethoxy)ethyl alcohol

: 98-59-9
p-toluenesulfonyl chloride

: 89346-82-7
2-<2-<2-<2-(benzyloxy)ethoxy>ethoxy>ethoxy>ethyl 4-methylbenzenesulfonate

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 15h; Cooling with ice;
DOI:10.1002/anie.201403436

Reference yield:

: 100-39-0
benzyl bromide

: 89346-82-7
2-<2-<2-<2-(benzyloxy)ethoxy>ethoxy>ethoxy>ethyl 4-methylbenzenesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / tetrahydrofuran / 12 h / Ambient temperature

2: pyridine / 0 °C

With pyridine; sodium hydride; In tetrahydrofuran;
DOI:10.1021/ja00091a005