2-Chloro-N-(phenylcarbamothioyl)pyridine-3-carboxamide

Base Information

Chemical Name:2-Chloro-N-(phenylcarbamothioyl)pyridine-3-carboxamide
CAS No.:89374-26-5
Molecular Formula:C13H10ClN3OS
Molecular Weight:291.761
Hs Code.:
DSSTox Substance ID:DTXSID00530231
Wikidata:Q82401231

Synonyms:89374-26-5;2-Chloro-N-(phenylcarbamothioyl)pyridine-3-carboxamide;SCHEMBL7097011;DTXSID00530231

Suppliers and Price of 2-Chloro-N-(phenylcarbamothioyl)pyridine-3-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-Chloro-N-(phenylcarbamothioyl)pyridine-3-carboxamide

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:291.0233108
Heavy Atom Count:19
Complexity:334

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)NC(=S)NC(=O)C2=C(N=CC=C2)Cl

Technology Process of 2-Chloro-N-(phenylcarbamothioyl)pyridine-3-carboxamide

There total 3 articles about 2-Chloro-N-(phenylcarbamothioyl)pyridine-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 89374-20-9
2-Chloronicotinoyl Isothiocyanate

: 62-53-3
aniline

: 89374-26-5
1-(2-Chloro-pyridine-3-carbonyl)-3-phenyl-thiourea

Guidance literature:: In acetone; at 20 ℃; for 0.5h;
DOI:10.1135/cccc19833315

Reference yield:

: 2942-59-8
2-chloronicotinic acid

: 89374-26-5
1-(2-Chloro-pyridine-3-carbonyl)-3-phenyl-thiourea

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride / 4 h / Reflux

2: acetone / 0.5 h / 20 °C

3: acetone / 5.5 h / 20 °C

With thionyl chloride; In acetone;

Reference yield:

: 49609-84-9
2-Chloronicotinoyl chloride

: 89374-26-5
1-(2-Chloro-pyridine-3-carbonyl)-3-phenyl-thiourea

Guidance literature:: Multi-step reaction with 2 steps

1: acetone / 0.08 h / 40 °C

2: 85 percent / acetone / 0.5 h / 20 °C

In acetone;
DOI:10.1135/cccc19833315