Technology Process of Silane, [[2-(bromomethyl)-4-methoxyphenyl]ethynyl]trimethyl-
There total 6 articles about Silane, [[2-(bromomethyl)-4-methoxyphenyl]ethynyl]trimethyl- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
carbon tetrabromide; triphenylphosphine;
In
diethyl ether;
for 4h;
DOI:10.1021/jo00183a018
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 99 percent / pyridine / 1.) 0 degC, 15 min 2.) room temperature, 12 h
2: 68 percent / AlCl3 / CS2 / 0.5 h / Ambient temperature
3: 95 percent / PCl5 / POCl3 / 2 h / 45 - 50 °C
4: 92 percent / NaNH2 / tetrahydrofuran; hexamethylphosphoric acid triamide / 1.) -78 degC 2.) 50 degC, 2 h
6: 72 percent / P(C6H5)3, CBr4 / diethyl ether / 4 h
With
pyridine; aluminium trichloride; carbon tetrabromide; phosphorus pentachloride; sodium amide; triphenylphosphine;
In
tetrahydrofuran; carbon disulfide; N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether; trichlorophosphate;
DOI:10.1021/jo00183a018
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 68 percent / AlCl3 / CS2 / 0.5 h / Ambient temperature
2: 95 percent / PCl5 / POCl3 / 2 h / 45 - 50 °C
3: 92 percent / NaNH2 / tetrahydrofuran; hexamethylphosphoric acid triamide / 1.) -78 degC 2.) 50 degC, 2 h
5: 72 percent / P(C6H5)3, CBr4 / diethyl ether / 4 h
With
aluminium trichloride; carbon tetrabromide; phosphorus pentachloride; sodium amide; triphenylphosphine;
In
tetrahydrofuran; carbon disulfide; N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether; trichlorophosphate;
DOI:10.1021/jo00183a018
