ETHYL 6-CHLORO-3-OXO-2,3-DIHYDRO-1H-INDAZOLE-1-CARBOXYLATE

Base Information

Chemical Name:ETHYL 6-CHLORO-3-OXO-2,3-DIHYDRO-1H-INDAZOLE-1-CARBOXYLATE
CAS No.:89438-39-1
Molecular Formula:C₁₀H₉ClN₂O₃
Molecular Weight:240.646
Hs Code.:
Mol file:89438-39-1.mol

Synonyms:6-CHLORO-2,3-DIHYDRO-3-OXO-1H-INDAZOLE-1-CARBOXYLIC ACID ETHYL ESTER;1H-Indazole-1-carboxylic acid,6-chloro-2,3-dihydro-3-oxo-,ethyl ester;ETHYL 6-CHLORO-3-OXO-2,3-DIHYDRO-1H-INDAZOLE-1-CARBOXYLATE;

Suppliers and Price of ETHYL 6-CHLORO-3-OXO-2,3-DIHYDRO-1H-INDAZOLE-1-CARBOXYLATE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
1H-INDAZOLE-1-CARBOXYLICACID,6-CHLORO-2,3-DIHYDRO-3-OXO-,ETHYLESTER 95
10g
$ 3025.00

Total 4 raw suppliers

Chemical Property of ETHYL 6-CHLORO-3-OXO-2,3-DIHYDRO-1H-INDAZOLE-1-CARBOXYLATE

Chemical Property:

PSA：64.35000
LogP:2.39990

Purity/Quality:

98%min ^*data from raw suppliers

1H-INDAZOLE-1-CARBOXYLICACID,6-CHLORO-2,3-DIHYDRO-3-OXO-,ETHYLESTER 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ETHYL 6-CHLORO-3-OXO-2,3-DIHYDRO-1H-INDAZOLE-1-CARBOXYLATE

There total 3 articles about ETHYL 6-CHLORO-3-OXO-2,3-DIHYDRO-1H-INDAZOLE-1-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 7364-29-6
6-Chlorindazolin-3-on

: 541-41-3
chloroformic acid ethyl ester

: 89438-39-1
6-Chloro-3-oxo-2,3-dihydro-indazole-1-carboxylic acid ethyl ester

Guidance literature:: With pyridine; for 2h; Heating;
DOI:10.1021/jm00372a011

Reference yield:

: 64415-09-4
4-Chloro-2-hydrazino-benzoic acid; hydrochloride

: 89438-39-1
6-Chloro-3-oxo-2,3-dihydro-indazole-1-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: conc. HCl / a) RT, overnight, b) 80 deg C, 6 h

2: 73 percent / pyridine / 2 h / Heating

With pyridine; hydrogenchloride;
DOI:10.1021/jm00372a011

Reference yield:

: 89-77-0
2-Amino-4-chlorobenzoic acid

: 89438-39-1
6-Chloro-3-oxo-2,3-dihydro-indazole-1-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) aq. HCl, NaNO₂, 2.) Na₂SO₃ / 1.) <10 deg C, 30 min, 2.) H₂O, RT, 2 h

2: conc. HCl / a) RT, overnight, b) 80 deg C, 6 h

3: 73 percent / pyridine / 2 h / Heating

With pyridine; hydrogenchloride; sodium sulfite; sodium nitrite;
DOI:10.1021/jm00372a011