2-(4-Methoxyanilino)benzene-1,3-dicarboxylic acid

Base Information

Chemical Name:2-(4-Methoxyanilino)benzene-1,3-dicarboxylic acid
CAS No.:89459-40-5
Molecular Formula:C15H13NO5
Molecular Weight:287.272
Hs Code.:
DSSTox Substance ID:DTXSID00539360
Wikidata:Q82415088

Synonyms:89459-40-5;2-(4-Methoxyanilino)benzene-1,3-dicarboxylic acid;DTXSID00539360

Suppliers and Price of 2-(4-Methoxyanilino)benzene-1,3-dicarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-Methoxyanilino)benzene-1,3-dicarboxylic acid

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:287.07937252
Heavy Atom Count:21
Complexity:356

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)NC2=C(C=CC=C2C(=O)O)C(=O)O

Technology Process of 2-(4-Methoxyanilino)benzene-1,3-dicarboxylic acid

There total 2 articles about 2-(4-Methoxyanilino)benzene-1,3-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 2902-65-0
2-iodoyl-1,3-benzenedicarboxylic acid

: 104-94-9
4-methoxy-aniline

: 89459-40-5
2-(4-Methoxy-phenylamino)-isophthalic acid

Guidance literature:: With N-ethylmorpholine;; copper(l) chloride; In benzene; for 1h; Heating;
DOI:10.1055/s-1985-31164

Reference yield:

: 39622-79-2
2-aminoisophthalic acid

: 89459-40-5
2-(4-Methoxy-phenylamino)-isophthalic acid

Guidance literature:: Multi-step reaction with 2 steps

2: 78 percent / N-ethylmorpholine / CuCl / benzene; various solvent(s) / 1 h / Heating

With N-ethylmorpholine;; copper(l) chloride; In benzene;
DOI:10.1055/s-1985-31164

Reference yield:

: 89459-40-5
2-(4-Methoxy-phenylamino)-isophthalic acid

: 89459-61-0
9-Amino-7-methoxy-acridine-4-carboxylic acid (2-dimethylamino-ethyl)-amide

Guidance literature:: Multi-step reaction with 4 steps

1: polyphosphoric acid / 1 h / 120 °C

2: SOCl₂ / 1 h / Heating

3: CH₂Cl₂ / 0.5 h / 20 °C

4: NH₃(g) / various solvent(s) / 0.25 h / 110 - 120 °C

With thionyl chloride; PPA; ammonia; In dichloromethane;
DOI:10.1021/jm00154a008