4-Methyl-2-oxo-1-phenyl-2,5-dihydro-1H-pyrrole-3-carbonitrile

Base Information

Chemical Name:4-Methyl-2-oxo-1-phenyl-2,5-dihydro-1H-pyrrole-3-carbonitrile
CAS No.:89516-27-8
Molecular Formula:C₁₂H₁₀N₂O
Molecular Weight:198.224
Hs Code.:
DSSTox Substance ID:DTXSID40520095
Wikidata:Q82383746

Synonyms:89516-27-8;DTXSID40520095;4-Methyl-2-oxo-1-phenyl-2,5-dihydro-1H-pyrrole-3-carbonitrile

Suppliers and Price of 4-Methyl-2-oxo-1-phenyl-2,5-dihydro-1H-pyrrole-3-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Methyl-2-oxo-1-phenyl-2,5-dihydro-1H-pyrrole-3-carbonitrile

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:198.079312947
Heavy Atom Count:15
Complexity:355

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C(=O)N(C1)C2=CC=CC=C2)C#N

Technology Process of 4-Methyl-2-oxo-1-phenyl-2,5-dihydro-1H-pyrrole-3-carbonitrile

There total 5 articles about 4-Methyl-2-oxo-1-phenyl-2,5-dihydro-1H-pyrrole-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5832-69-9
2-Cyan-3-methyl-glutaconsaeure-ethylester

: 89516-27-8
3-Cyano-4-methyl-1-phenyl-3-pyrrolin-2-on

Guidance literature:: Multi-step reaction with 3 steps

1: 82 percent / aq. CH₃COONa / ethanol / 0.17 h

2: zinc dust, glac. CH₃COOH / 0.25 h

3: conc. HCl / acetic acid / 5 h / Heating

With hydrogenchloride; sodium acetate; acetic acid; zinc; In ethanol; acetic acid;
DOI:10.1055/s-1984-30732

Reference yield:

: 100-34-5
benzene diazonium chloride

: 89516-27-8
3-Cyano-4-methyl-1-phenyl-3-pyrrolin-2-on

Guidance literature:: Multi-step reaction with 3 steps

1: 82 percent / aq. CH₃COONa / ethanol / 0.17 h

2: zinc dust, glac. CH₃COOH / 0.25 h

3: conc. HCl / acetic acid / 5 h / Heating

With hydrogenchloride; sodium acetate; acetic acid; zinc; In ethanol; acetic acid;
DOI:10.1055/s-1984-30732

Reference yield:

: 89516-24-5
ethyl 5-cyano-4-methyl-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate

: 89516-27-8
3-Cyano-4-methyl-1-phenyl-3-pyrrolin-2-on

Guidance literature:: Multi-step reaction with 2 steps

1: zinc dust, glac. CH₃COOH / 0.25 h

2: conc. HCl / acetic acid / 5 h / Heating

With hydrogenchloride; acetic acid; zinc; In acetic acid;
DOI:10.1055/s-1984-30732