5-(2,4-Dichlorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-oxazolidin-2-one

Base Information

Chemical Name:5-(2,4-Dichlorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-oxazolidin-2-one
CAS No.:89544-78-5
Molecular Formula:C₁₂H₁₀Cl₂N₄O₂
Molecular Weight:313.143
Hs Code.:
DSSTox Substance ID:DTXSID00563201
Nikkaji Number:J339.693B

Synonyms:89544-78-5;SCHEMBL10910788;DTXSID00563201;BWXSBDZSIAWNSD-UHFFFAOYSA-N;5-(2,4-Dichlorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-oxazolidin-2-one;5-(2,4-Dichlorophenyl)-5-(1H-1,2,4-triazol-1-yl-methyl)-1,3-oxazolidin-2-on

Suppliers and Price of 5-(2,4-Dichlorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-oxazolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(2,4-Dichlorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-oxazolidin-2-one

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:312.0180810
Heavy Atom Count:20
Complexity:387

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(OC(=O)N1)(CN2C=NC=N2)C3=C(C=C(C=C3)Cl)Cl

Technology Process of 5-(2,4-Dichlorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-oxazolidin-2-one

There total 4 articles about 5-(2,4-Dichlorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-oxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 89544-54-7
1-[3-Amino-2-(2,4-dichlorophenyl)-2-hydroxyprop-1-yl]-1H-1,2,4-triazole

: 530-62-1
1,1'-carbonyldiimidazole

petrol: petrol

: 89544-78-5
5-(2,4-Dichlorophenyl)-5-(1H-1,2,4-triazol-1-yl-methyl)-1,3-oxazolidin-2-on

Guidance literature:: In tetrahydrofuran; ethyl acetate;

Reference yield:

: 132507-95-0,81886-66-0
1,2-epoxy-2-(2,4-dichlorophenyl)-3-(1,2,4-triazol-1-yl)-propane

: 89544-78-5
5-(2,4-Dichlorophenyl)-5-(1H-1,2,4-triazol-1-yl-methyl)-1,3-oxazolidin-2-on

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / NaN₃, NH₄Cl / dimethylformamide / 1.5 h / 90 °C

2: 98 percent / H₂ / 10percent Pd/C / ethanol / 1 h / Ambient temperature

3: DMAP / CH₂Cl₂ / 0.33 h / -15 °C

With dmap; sodium azide; hydrogen; ammonium chloride; palladium on activated charcoal; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.38.2476

Reference yield:

: 89544-81-0
1-[3-Azido-2-(2,4-dichlorophenyl)-2-hydroxyprop-1-yl]-1H-1,2,4-triazole

: 89544-78-5
5-(2,4-Dichlorophenyl)-5-(1H-1,2,4-triazol-1-yl-methyl)-1,3-oxazolidin-2-on

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / H₂ / 10percent Pd/C / ethanol / 1 h / Ambient temperature

2: DMAP / CH₂Cl₂ / 0.33 h / -15 °C

With dmap; hydrogen; palladium on activated charcoal; In ethanol; dichloromethane;
DOI:10.1248/cpb.38.2476