Phenylmethyl (4S)-5-oxo-4-(3-oxopentyl)-3-oxazolidinecarboxylate

Base Information

Chemical Name:Phenylmethyl (4S)-5-oxo-4-(3-oxopentyl)-3-oxazolidinecarboxylate
CAS No.:89662-52-2
Molecular Formula:C16H19NO5
Molecular Weight:305.331
Hs Code.:
DSSTox Substance ID:DTXSID201172781

Synonyms:SCHEMBL9536587;DTXSID201172781;Phenylmethyl (4S)-5-oxo-4-(3-oxopentyl)-3-oxazolidinecarboxylate;89662-52-2

Suppliers and Price of Phenylmethyl (4S)-5-oxo-4-(3-oxopentyl)-3-oxazolidinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Phenylmethyl (4S)-5-oxo-4-(3-oxopentyl)-3-oxazolidinecarboxylate

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:305.12632271
Heavy Atom Count:22
Complexity:417

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=O)CCC1C(=O)OCN1C(=O)OCC2=CC=CC=C2
Isomeric SMILES:CCC(=O)CC[C@H]1C(=O)OCN1C(=O)OCC2=CC=CC=C2

Technology Process of Phenylmethyl (4S)-5-oxo-4-(3-oxopentyl)-3-oxazolidinecarboxylate

There total 6 articles about Phenylmethyl (4S)-5-oxo-4-(3-oxopentyl)-3-oxazolidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 23632-67-9
(S)-3-[3-(benzyloxycarbonyl)-5-oxooxazolidin-4-yl]propanoic acid

: 89662-52-2
(4S)-3-Benzyloxycarbonyl-4-(3'-oxopentyl)oxazolidin-5-one

Guidance literature:: Multi-step reaction with 4 steps

1: N-methylmorpholine / tetrahydrofuran / 0.5 h / -15 °C

2: Et₃N / tetrahydrofuran / 1 h / -15 °C

3: iodoform / 1,1,1-trichloro-ethane / 3 h / Irradiation

4: 1.) Zn, 1,2-dibromoethane, Me₃SiCl / 2.) PdCl₂(PPh₃)2 / 1.) 1,2-DME, 35 deg C, 15 min, 2.) 1,2-DME, 35 deg C, 1 h

With 4-methyl-morpholine; chloro-trimethyl-silane; iodoform; ethylene dibromide; triethylamine; zinc; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; 1,1,1-trichloroethane;
DOI:10.1039/a802142b

Reference yield:

: (S)-4-(3-Isobutoxycarbonyloxy-3-oxo-propyl)-5-oxo-oxazolidine-3-carboxylic acid benzyl ester

: 89662-52-2
(4S)-3-Benzyloxycarbonyl-4-(3'-oxopentyl)oxazolidin-5-one

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N / tetrahydrofuran / 1 h / -15 °C

2: iodoform / 1,1,1-trichloro-ethane / 3 h / Irradiation

3: 1.) Zn, 1,2-dibromoethane, Me₃SiCl / 2.) PdCl₂(PPh₃)2 / 1.) 1,2-DME, 35 deg C, 15 min, 2.) 1,2-DME, 35 deg C, 1 h

With chloro-trimethyl-silane; iodoform; ethylene dibromide; triethylamine; zinc; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; 1,1,1-trichloroethane;
DOI:10.1039/a802142b

Reference yield:

: (S)-5-Oxo-4-[2-(pyridin-2-ylsulfanylcarbonyl)-ethyl]-oxazolidine-3-carboxylic acid benzyl ester

: 89662-52-2
(4S)-3-Benzyloxycarbonyl-4-(3'-oxopentyl)oxazolidin-5-one

Guidance literature:: Multi-step reaction with 2 steps

1: iodoform / 1,1,1-trichloro-ethane / 3 h / Irradiation

2: 1.) Zn, 1,2-dibromoethane, Me₃SiCl / 2.) PdCl₂(PPh₃)2 / 1.) 1,2-DME, 35 deg C, 15 min, 2.) 1,2-DME, 35 deg C, 1 h

With chloro-trimethyl-silane; iodoform; ethylene dibromide; zinc; bis-triphenylphosphine-palladium(II) chloride; In 1,1,1-trichloroethane;
DOI:10.1039/a802142b