23632-67-9

Basic information

• Product Name: (S)-(+)-3-(BENZYLOXYCARBONYL)-5-OXO-4-OXAZOLIDINEPROPIONIC ACID
• Synonyms: (S)-3-BENZYLOXYCARBONYL-5-OXO-4-OXAZOLIDINEPROPANOIC ACID;(S)-(+)-3-(BENZYLOXYCARBONYL)-5-OXO-4-OXAZOLIDINEPROPIONIC ACID;4-(S)-(2-CARBOXY-ETHYL)-5-OXO-OXAZOLIDINE-3-CARBOXYLIC ACID BENZYL ESTER;(4S)-5-Oxo-3-[(phenylMethoxy)carbonyl]-4-oxazolidinepropanoic Acid;3-{(4S)-3-[(benzyloxy)carbonyl]-5-oxo-1,3-oxazolidin-4-yl}propanoic acid;(S)-(+)-3-(Benzyloxycarbonyl)-5-oxo-4-oxazolidinepropionic acid 97%;(S)-3-(3-((benzyloxy)carbonyl)-5-oxooxazolidin-4 -yl)propanoic acid
• CAS NO: 23632-67-9
• Molecular Formula: C₁₄H₁₅NO₆
• Molecular Weight: 293.27
• Product Categories: Miscellaneous Reagents;Asymmetric Synthesis;Chiral Auxiliaries;Oxazolidinone Derivatives;Chiral Reagents;Heterocycles
• Mol File: 23632-67-9.mol
• Article Data: 30

Chemical Properties

• Melting Point: 68-69 °C
• Boiling Point: 557.2 °C at 760 mmHg
• Flash Point: >230 °F
• Appearance: /
• Density: 1.05 g/mL at 25 °C(lit.)
• Vapor Pressure: 2.98E-13mmHg at 25°C
• Refractive Index: n20/D 1.535(lit.)
• Storage Temp.: ?20°C
• Solubility: Dichloromethane, Ethyl Acetate, Methanol
• PKA: 4.53±0.10(Predicted)
• CAS DataBase Reference: (S)-(+)-3-(BENZYLOXYCARBONYL)-5-OXO-4-OXAZOLIDINEPROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(+)-3-(BENZYLOXYCARBONYL)-5-OXO-4-OXAZOLIDINEPROPIONIC ACID(23632-67-9)
• EPA Substance Registry System: (S)-(+)-3-(BENZYLOXYCARBONYL)-5-OXO-4-OXAZOLIDINEPROPIONIC ACID(23632-67-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 23632-67-9(Hazardous Substances Data)

Usage

Chemical Properties

Colourless Gel

InChI:InChI=1/C14H15NO6/c16-12(17)7-6-11-13(18)21-9-15(11)14(19)20-8-10-4-2-1-3-5-10/h1-5,11H,6-9H2,(H,16,17)/t11-/m0/s1

Upstream product

• 110-88-3 1,3,5-Trioxan 
• 1155-62-0 N-benzyloxycarbonyl-L-glutamic acid 
• 50-00-0 formaldehyd 
• 501-53-1 benzyl chloroformate 
• 75-75-2 methanesulfonic acid 
• 56-86-0 L-glutamic acid 
• 241823-95-0 (S)-4-{2-[Bis-(4-fluoro-phenyl)-pentafluorophenyl-methoxycarbonyl]-ethyl}-5-oxo-oxazolidine-3-carboxylic acid benzyl ester 

Downstream Products

• 23632-68-0 4(S)-(2-tert-butoxycarbonylethyl)-5-oxo-oxazolidine 3-carboxylic acid benzyl ester 
• 56202-06-3 Z-Glu-NPr₂ 
• 5672-83-3 Z-L-GluOMe 
• 203919-89-5 (S)-5-Oxo-4-[2-(2-trimethylsilanyl-ethoxycarbonyl)-ethyl]-oxazolidine-3-carboxylic acid benzyl ester 
• 241823-95-0 (S)-4-{2-[Bis-(4-fluoro-phenyl)-pentafluorophenyl-methoxycarbonyl]-ethyl}-5-oxo-oxazolidine-3-carboxylic acid benzyl ester 
• 56-86-0 L-glutamic acid 
• 922705-84-8 (2S)-2-(methyl{[(phenylmethyl)oxy]carbonyl}amino)-5-oxo-5-[(phenylmethyl)oxy]pentanoic acid 
• 922705-86-0 phenylmethyl (4S)-6-diazo-4-(methyl{[(phenylmethyl)oxy]carbonyl}amino)-5-oxohexanoate 
• 922705-89-3 (3S)-3-(methyl{[(phenylmethyl)oxy]carbonyl}amino)-6-oxo-6-[(phenylmethyl)oxy]hexanoic acid 
• 914939-81-4 (2S)-5-[bis(phenylmethyl)amino]-2-(methyl{[(phenylmethyl)oxy]carbonyl}amino)-5-oxopentanoic acid 
• 203585-49-3 phenylmethyl (4S)-4-{3-[bis(phenylmethyl)amino]-3-oxopropyl}-5-oxo-1,3-oxazolidine-3-carboxylate 
• 914939-82-5 phenylmethyl {(1S)-4-[bis(phenylmethyl)amino]-1-(diazoacetyl)-4-oxobutyl}methylcarbamate 
• 914939-83-6 (3S)-6-[bis(phenylmethyl)amino]-3-(methyl{[(phenylmethyl)oxy]carbonyl}amino)-6-oxohexanoic acid 
• 82361-46-4 (2R,6S)-2-Benzyloxycarbonylamino-6-tert-butoxycarbonylamino-heptanedioic acid 7-methyl ester 

Relevant articles and documents

A NOVEL AND EFFICIENT SYNTHESIS OF L-VINYLGLYCINE

A simple and practical synthesis of the title compound starting with L-glutamic acid is described.

PROCESSES FOR PREPARATION OF (S)-TERT-BUTYL 4,5-DIAMINO-5-OXOPENTANOATE

Provided are processes for the preparation of (S)-tert-butyl 4,5-diamino-5-oxopentanoate, or a salt, solvate, hydrate, enantiomer, mixture of enantiomers, or isotopologue thereof. Also provided are solid forms of various intermediates and products obtained from the processes.

Synthesis of N -[(3 S)-2,6-dioxo-1-(2-phenylethyl)-3-piperidinyl]-(2 S)-2-methylbutanamide (( - )-julocrotine)

The total synthesis of ( - )-julocrotine (1) starting from l-glutamic acid in 41% overall yield is described. The methodology utilizes protection, deprotection, and regioselection (carbonyl differentiation via oxazolidinone) protocols, and glutarimide ring formation is the key step.