Phenophosphazine, 5,10-dihydro-5-methyl-10-phenyl-

Base Information

• Chemical Name: Phenophosphazine, 5,10-dihydro-5-methyl-10-phenyl-
• CAS No.: 896-84-4
• Molecular Formula: C19H16NP
• Molecular Weight: 289.317
• Mol file: 896-84-4.mol

Synonyms:

Chemical Property of Phenophosphazine, 5,10-dihydro-5-methyl-10-phenyl-

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phenophosphazine, 5,10-dihydro-5-methyl-10-phenyl-

There total 9 articles about Phenophosphazine, 5,10-dihydro-5-methyl-10-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Dichlorophenylphosphine (644-97-3) + 5,10,10-trimethyl-5,10-dihydrophenazastannin (17154-51-7) → dimethyltin dichloride (753-73-1) + 5-methyl-10-phenyl-5,10-dihydrophenophosphazinine (896-84-4)

Guidance literature:

180.degreeC, 2h;;

DOI:10.1016/S0022-328X(00)81731-3

Reference yield:

2-bromo-N-(2-(diphenylphosphino)phenyl)-N-methylaniline → 5-methyl-10-phenyl-5,10-dihydrophenophosphazinine (896-84-4)

Guidance literature:

With tris-(trimethylsilyl)silane; palladium diacetate; In N,N-dimethyl-formamide; at 130 ℃; for 12h; Inert atmosphere; Sealed tube;

DOI:10.1021/ol503252t

Reference yield:

(2'-bromophenyl)-(2-nitrophenyl)-amine (58476-60-1) → 5-methyl-10-phenyl-5,10-dihydrophenophosphazinine (896-84-4)

Guidance literature:

Multi-step reaction with 5 steps

1: dimethyl sulfoxide / 3 h / Inert atmosphere; Sealed tube

2: iron; ammonium chloride / ethanol; water / 3 h / Sealed tube; Reflux

3: sodium nitrite; potassium iodide; toluene-4-sulfonic acid / water; acetonitrile / 0 - 20 °C / Sealed tube

4: copper(l) iodide; caesium carbonate / toluene / 48 h / 110 °C / Sealed tube; Inert atmosphere

5: tris-(trimethylsilyl)silane; palladium diacetate / N,N-dimethyl-formamide / 12 h / 130 °C / Inert atmosphere; Sealed tube

With copper(l) iodide; tris-(trimethylsilyl)silane; palladium diacetate; iron; ammonium chloride; caesium carbonate; toluene-4-sulfonic acid; potassium iodide; sodium nitrite; In ethanol; water; dimethyl sulfoxide; N,N-dimethyl-formamide; toluene; acetonitrile;

DOI:10.1021/ol503252t

upstream raw materials:

Dichlorophenylphosphine

5,10,10-trimethyl-5,10-dihydrophenazastannin

2,2'-dilithiodiphenyl-N-methylamine

(2'-bromophenyl)-(2-nitrophenyl)-amine

Downstream raw materials:

5-methyl-10-phenyl-5,10-dihydrophenophosphazinine 10-oxide

Refernces