Technology Process of 3,7-diphenyl-5,6-dihydro-4H-1,2-diazepine
There total 7 articles about 3,7-diphenyl-5,6-dihydro-4H-1,2-diazepine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
5-(tert-butylperoxy)-1,5-diphenylpentan-1-one;
With
1,8-diazabicyclo[5.4.0]undec-7-ene;
In
acetonitrile;
at 50 ℃;
for 1h;
Schlenk technique;
With
hydrazine hydrate;
In
ethanol;
at 80 ℃;
for 12h;
Schlenk technique;
DOI:10.1021/acs.orglett.1c02824
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: iron(III)-acetylacetonate / 1,2-dichloro-ethane / 8 h / 70 °C / Inert atmosphere; Schlenk technique
2.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 1 h / 50 °C / Schlenk technique
2.2: 12 h / 80 °C / Schlenk technique
With
iron(III)-acetylacetonate; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
1,2-dichloro-ethane; acetonitrile;
DOI:10.1021/acs.orglett.1c02824
